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CYTOCHALASIN B

CYTOCHALASIN B Suppliers list
Company Name: Dalian Meilun Biotech Co., Ltd.  Gold
Tel: 0411-66771943;0411-66771942
Email: sales@meilune.com
Products Intro: Product Name:Cytochalasin B
CAS:14930-96-2
Purity:>96% Package:590RMB/1MG
Company Name: Beijing Solarbio Science & Tecnology Co., Ltd.  Gold
Tel: 010-56371205 56371220
Email: solarbio@163.com
Products Intro: Product Name:Cytochalasin B
CAS:14930-96-2
Package:1mg
Company Name: Hefei Bomei Biotechnology Co., Ltd.  Gold
Tel: 13739298932
Email: 531626407@qq.com
Products Intro: Product Name:Cytochalasin B
CAS:14930-96-2
Purity:Purity>=98%(HPLC) Package:1mg 5mg:580.00 1760.00
Company Name: J & K SCIENTIFIC LTD.  
Tel: 400-666-7788 +86-10-82848833
Email: jkinfo@jkchemical.com;market6@jkchemical.com
Products Intro: Product Name:Cytochalasin B, 98%, from Drechslera dematoidea
CAS:14930-96-2
Purity:98% Package:1MG;25MG;5MG
Company Name: Meryer (Shanghai) Chemical Technology Co., Ltd.  
Tel: +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
Email: sh@meryer.com
Products Intro: Product Name:Cytochalasin B
CAS:14930-96-2
Remarks:22809
CYTOCHALASIN B Basic information
Product Name:CYTOCHALASIN B
Synonyms:CytochalasinB from Drechslera dematioidea,Phomin;Cytochalasin B, froM Drechslera deMatoidea;Cytochalasin B (7S),(20R)-Dihydroxy-16(R)-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13(E),21(E)-triene-1,23-dione;Cytochalasin B from Helminthosporium dematioideum ;cytochalasin;ec[2,3-d]isoindole-2,18(5h)-dione;(E,E)-16-BENZYL-6,7,8,9,10,12A,13,14,15,15A,16,17-DODECAHYDRO-5,13-DIHYDROXY-9,15-DIMETHYL-14-METHYLENE-2H-OXACYCLOTETRADE[2,3-D]ISOINDOLE-2,18(5H)-DIONE;CYTOCHALASIN B, HELMINTHOSPORIUM DEMATIOIDEUM
CAS:14930-96-2
MF:C29H37NO5
MW:479.61
EINECS:239-000-2
Product Categories:antibiotic
Mol File:14930-96-2.mol
CYTOCHALASIN B Structure
CYTOCHALASIN B Chemical Properties
Melting point 218-223 °C
Boiling point 577.96°C (rough estimate)
density 1.1490 (rough estimate)
refractive index 1.6290 (estimate)
Fp 85℃
storage temp. −20°C
solubility ethanol: 20 mg/mL
form powder
color white
Merck 13,2819
BRN 1096207
EPA Substance Registry System2H-Oxacyclotetradecino[ 2,3-d]isoindole-2,18(5H)- dione, 6,7,8,9,10,12a,13,14,15,15a, 16,17-dodecahydro-5,13-dihydroxy- 9,15-dimethyl-14-methylene- 16-(phenylmethyl)-, (3E,5R,9R,11E,12aS,13S,15S, 15aS,16S,18aS)-(14930-96-2)
Safety Information
Hazard Codes T+,T
Risk Statements 26/27/28-63-23/24/25
Safety Statements 28-36/37-45
RIDADR UN 1544 6.1/PG 2
WGK Germany 3
RTECS RO0205000
10
HazardClass 6.1(a)
PackingGroup I
HS Code 29349990
Hazardous Substances Data14930-96-2(Hazardous Substances Data)
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
CYTOCHALASIN B Usage And Synthesis
Chemical Propertieswhite to off-white powder
UsesCytochalasin B is one of the most extensively studied members of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, giving rise to pronounced morphogenic activity in animals and plants. Like most cytochalsins, cytochalasin B exhibits potent inhibition of actin filament function leading to cell death by apoptosis, and displays a broad range of resultant cellular actions. Despite the common mode of action, there is evidence that individual members of this class display diverse selectivity. However, lack of comparative co-metabolite analysis has restricted a more complete understanding of their individual selectivity.
UsesCytochalasin B is one of the most extensively studied members of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, giving rise to pronounced morphogenic activity in animals and plants. Like most cytochalasins, cytochalasin B exhibits potent inhibition of actin filament function leading to cell death by apoptosis, and displays a broad range of resultant cellular actions. Despite the common mode of action, there is evidence that individual members of this class display diverse selectivity. However, lack of comparative co-metabolite analysis has restricted a more complete understanding of their individual selectivity.
UsesA cell-permeable fungal toxin used in actin polymerization studies and cytological
UsesAs tools in cytological research and in characterization of polymerization properties of actin, q.v.
DefinitionChEBI: An organic heterotricyclic compound, that is a mycotoxin which is cell permeable an an inhibitor of cytoplasmic division by blocking the formation of contractile microfilaments.
Purification MethodsPurify it by MeOH extraction, reverse phase C18 silica gel batch extraction by selective elution with 1:1 v/v hexane/tetrahydrofuran, crystallisation, subjected to TLC and recrystallisation [Lipski et al. Anal Biochem 161 332 1987]. It is soluble in EtOH (3.6%), Me2CO (1%), Me2SO (37%) and Me2NCHO (49%) at 24o, and can be crystallised from the first two solvents. It interferes with cellular movement [Korm Physiol Reviews 62 672 1982].
CYTOCHALASIN B Preparation Products And Raw materials
Tag:CYTOCHALASIN B(14930-96-2) Related Product Information
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