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| | 2-Fluoro-3-pyridylboronic acid Basic information |
| | 2-Fluoro-3-pyridylboronic acid Chemical Properties |
| Melting point | 274-283 °C | | Boiling point | 322.6±52.0 °C(Predicted) | | density | 1.34±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | solubility | soluble in Methanol | | form | solid | | pka | 6.68±0.58(Predicted) | | color | white | | BRN | 9119935 | | InChI | 1S/C5H5BFNO2/c7-5-4(6(9)10)2-1-3-8-5/h1-3,9-10H | | InChIKey | YUHZIUAREWNXJT-UHFFFAOYSA-N | | SMILES | OB(O)c1cccnc1F | | CAS DataBase Reference | 174669-73-9(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | TSCA | No | | HazardClass | IRRITANT | | HS Code | 29333990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| Provider | Language |
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ALFA
| English |
| | 2-Fluoro-3-pyridylboronic acid Usage And Synthesis |
| Chemical Properties | White powder | | Uses | Reactant involved in:
- Heterocyclization eith α-oxocarboxylic acids
- Suzuki-Miyaura coupling reactions
Additionally used as a precursor to biologically active molecules including:
- Heteroaryl benzylureas with glycogen synthase kinase 3 inhibitory activity
- Carboxyindoles with HCV NS5B polymerase inhibitory activity
- Pyrazolyl- and thienyl-aminohydantoins with BACE1 inhibitory activity
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| | 2-Fluoro-3-pyridylboronic acid Preparation Products And Raw materials |
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