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ACETYLSHIKONIN

ACETYLSHIKONIN Suppliers list
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Acetylshikonin
CAS:24502-78-1
Purity:HPLC>=98% Package:20mg
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:ACETYLSHIKONIN
CAS:24502-78-1
Purity:99% Package:1KG;1USD
Company Name: Chengdu GLP biotechnology Co Ltd
Tel: 028-87075086
Email: scglp@glp-china.com
Products Intro: Product Name:Acetylshikonin
CAS:24502-78-1
Purity:0.98 Package:20MG;50MG;100MG;1G;5G;1KG
Company Name: Chengdu Biopurify Phytochemicals Ltd.
Tel: 18080483897
Email: maggie@biopurify.com
Products Intro: Product Name:Acetylshikonin
CAS:24502-78-1
Purity:90%~98% HPLC Package:20mg;100mg;500mg;1g Remarks:BP0118
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-18871470254
Email: linda@hubeijusheng.com
Products Intro: Product Name:ACETYLSHIKONIN
CAS:24502-78-1
Purity:0.99 Package:5KG;1KG Remarks:C18H18O6

Lastest Price from ACETYLSHIKONIN manufacturers

  • Acetylshikonin
  • US $0.00 / mg
  • 2020-05-26
  • CAS:24502-78-1
  • Min. Order: 20mg
  • Purity: ≥98%(HPLC)
  • Supply Ability: 10 g
  • ACETYLSHIKONIN
  • US $1.00 / KG
  • 2019-07-06
  • CAS:24502-78-1
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: Customized
ACETYLSHIKONIN Basic information
Product Name:ACETYLSHIKONIN
Synonyms:(+)-5,8-Dihydroxy-2-[(R)-1-acetoxy-4-methyl-3-pentenyl]-1,4-naphthoquinone;(R)-1-(1,4-Dihydro-5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methyl-3-pentenyl=acetate;2-[(R)-1-Acetoxy-4-methyl-3-pentenyl]-5,8-dihydroxy-1,4-naphthoquinone;O-Acetylshikonin;1,4-Naphthoquinone, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-, 2-acetate, (+)-;Nsc110199;Shikonin, acetyl;Shikonin acetate
CAS:24502-78-1
MF:C18H18O6
MW:330.33
EINECS:
Product Categories:Miscellaneous Natural Products
Mol File:24502-78-1.mol
ACETYLSHIKONIN Structure
ACETYLSHIKONIN Chemical Properties
Melting point 86°C
Boiling point 553.2±50.0 °C(Predicted)
density 1.326±0.06 g/cm3(Predicted)
pka7.12±0.20(Predicted)
CAS DataBase Reference24502-78-1(CAS DataBase Reference)
Safety Information
Risk Statements 36/37/38
Safety Statements 26-36/37/39
MSDS Information
ACETYLSHIKONIN Usage And Synthesis
Chemical PropertiesAcetylshikonin is a biologically active compound with anti-cancer and anti-inflammatory activity, which is isolated from the roots of Lithospermum erythrorhizoma.
Biological ActivityAcetylshikonin is one naphthoquinone derivative isolated from the Lithospermum erythrorhizon, exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC50 of over 20 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and angiogenic factors.
Acetylshikonin inhibits the generation of NADPH oxidase complex in the activation of respiratory burst of PMNs, but does not directly inhibit the activity of NADPH oxidase already generated.
Certain shikonin derivatives(such as Acetyl shikonin) act as modulators of the Nur77-mediated apoptotic pathway and identify a new shikonin-based lead that targets Nur77 for apoptosis induction.
Acetylshikonin, shikonin, and alkannin have accelerative effect on the proliferation of granulation tissue in rats.
Acetylshikonin isolated from Arnebia euchroma (Royle) Johnst cell suspension cultures exhibits specific in vivo and in vitro antitumor effects.
Acetylshikonin has inhibitory effect on the edematous response is due neither to the release of steroid hormones from the adrenal gland nor to the glucocorticoid activity, but probably partly to the suppression of mast cell degranulation and partly to protection of the vasculature from mediator challenge.
Acetylshikonin induces apoptosis of hepatitis B virus X protein-expressing human hepatocellular carcinoma cells via endoplasmic reticulum stress.
ACETYLSHIKONIN Preparation Products And Raw materials
Tag:ACETYLSHIKONIN(24502-78-1) Related Product Information
Kaempferol Myricetin Diosgenin Isorhamnetin Taxifolin ARTEMISININ Atractylodin Neohesperidosyl dihydrochalcone Bengenin PINOCEMBRIN Alkannin 5,8-Dihydroxy-1,4-naphthoquinone ISOVALERYLSHIKONIN ISOBUTYRYLSHIKONIN (BETA,BETA-DIMETHYLACRYL)SHIKONIN ACETYLSHIKONIN (2-METHYL-N-BUTYRYL)SHIKONIN BETA-HYDROXYISOVALERYLSHIKONIN