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| | 6-Hydroxy-2-naphthoic acid Basic information |
| | 6-Hydroxy-2-naphthoic acid Chemical Properties |
| Melting point | 240-250 °C (lit.) | | Boiling point | 283.17°C (rough estimate) | | density | 1.2100 (rough estimate) | | vapor pressure | 0Pa at 25℃ | | refractive index | 1.6400 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Insoluble in water | | form | Powder | | pka | 4.34±0.30(Predicted) | | color | Pale brown | | Water Solubility | 99mg/L at 20℃ | | BRN | 2692084 | | LogP | 2.1 | | CAS DataBase Reference | 16712-64-4(CAS DataBase Reference) | | EPA Substance Registry System | 6-Hydroxy-2-naphthoic acid (16712-64-4) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 37/39-26-24/25 | | WGK Germany | 3 | | RTECS | QN3722500 | | TSCA | Yes | | HS Code | 29181990 | | Toxicity | rat,LD50,oral,3080mg/kg (3080mg/kg),PERIPHERAL NERVE AND SENSATION: SENSORY CHANGE INVOLVING PERIPHERAL NERVEGASTROINTESTINAL: OTHER CHANGESLUNGS, THORAX, OR RESPIRATION: OTHER CHANGES,National Technical Information Service. Vol. OTS0534748, |
| | 6-Hydroxy-2-naphthoic acid Usage And Synthesis |
| Chemical Properties | pale brown powder | | Uses | 6-Hydroxy-2-naphthoic acid may be used in the synthesis of 5-bromo-6-hydroxy-2-naphthoic acid and liquid-crystalline epoxy resins. | | Uses | 6-hydroxy-2-naphthoic acid is used for preparation engineering plastics, organic pigments, liquid crystal materials, medicine, particularly as a monomer of heat-resistant material. | | Definition | ChEBI: 6-Hydroxy-2-naphthoic acid is a naphthoic acid. | | General Description | 6-Hydroxy-2-naphthoic acid is a hydroxynaphthoic acid derivative. Whole cells of the recombinant Escherichia coli strain expressing CYP199A2 were reported to catalyze the regioselective oxidation of 6-hydroxy-2-naphthoic acid to afford 6,7-dihydroxynaphthoic acid. It can form co-crystals with caffeine. | | Flammability and Explosibility | Non flammable | | Synthesis | 6-Hydroxy-2-naphthoic acid [16712-64-4], mp 245 – 248℃, is synthesized by carboxylation of the potassium salt of 2-naphthol at 170 – 230℃. It couples with diazo compounds in the 5-position and undergoes sulfonation in the 4- and 7-positions. |
| | 6-Hydroxy-2-naphthoic acid Preparation Products And Raw materials |
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