|
| (R)-4-Chloro-3-hydroxybutyronitrile Basic information |
| (R)-4-Chloro-3-hydroxybutyronitrile Chemical Properties |
alpha | 11 º (neat) | Boiling point | 110 °C1 mm Hg(lit.) | density | 1.250 g/mL at 20 °C(lit.) | refractive index | n20/D 1.474(lit.) | Fp | >230 °F | storage temp. | Inert atmosphere,Room Temperature | pka | 12.67±0.20(Predicted) | form | clear liquid | color | Colorless to Light yellow | optical activity | [α]25/D +11.0°, neat | BRN | 1700586 | CAS DataBase Reference | 84367-31-7(CAS DataBase Reference) |
| (R)-4-Chloro-3-hydroxybutyronitrile Usage And Synthesis |
Chemical Properties | Colorless to pale yellow liquid | Uses | (R)-(+)-4-Chloro-3-hydroxybutyronitrile is a chiral reagent used in asymmetric catalysis in organic synthesis. | Uses | (-)-Carnitine and (-)-γ-amino-β-hydroxybutyric acid have been prepared using this synthon. |
| (R)-4-Chloro-3-hydroxybutyronitrile Preparation Products And Raw materials |
Raw materials | (1-chloro-3-cyano-propan-2-yl) acetate-->2-Propanol, 1-bromo-3-chloro-, 2-acetate, (2S)--->1,3,2-Dioxathiolane, 4-(chloromethyl)-, 2-oxide, (4R)--->(S)-4-Chloro-3-hydroxybutyronitrile | Preparation Products | Butanamide, 4-chloro-3-hydroxy-, (3R)- |
|