- LEE011 (succinate)
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- $10.00 / 1Kg/Bag
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2022-02-25
- CAS:1374639-75-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 Tons
- LEE011 (succinate)
-
- $1.00 / 1kg
-
2019-07-06
- CAS:1374639-75-4
- Min. Order: 1kg
- Purity: 95%-99%
- Supply Ability: 100kg
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| | LEE011 (succinate) Basic information |
| Product Name: | LEE011 (succinate) | | Synonyms: | LEE011 (succinate);7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide succinate;LEE-011 succinate salt, Ribociclib succinate salt;Ribociclib Succinate (Kisqali);RIBOCICLIB SUCCINATE (LEE011 SUCCINATE);Ribociclib succite;1374639-75-4 LEE011 (succinate);Ribociclib succinate | | CAS: | 1374639-75-4 | | MF: | C27H36N8O5 | | MW: | 552.64 | | EINECS: | | | Product Categories: | | | Mol File: | 1374639-75-4.mol |  |
| | LEE011 (succinate) Chemical Properties |
| Melting point | >160oC (dec.) | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | color | Pale Beige |
| | LEE011 (succinate) Usage And Synthesis |
| Uses | LEE011 is an orally bioavailable and highly specific CDK4/6 (cyclin-dependent kinase 4/6) inhibitor. LEE011 in combination with LGX818 (a V600E BRAF specific inhibitor) or BYL719 (a PIK3CA specific inhibitor) leads to robust anti-tumor activity in melanoma and breast cancer tumor models. |
| | LEE011 (succinate) Preparation Products And Raw materials |
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