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Glycolic acid

Glycolic acid Suppliers list
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Glycolic acid manufacturers

  • Glycolic acid
  • Glycolic acid pictures
  • $1.00 / 1g
  • 2024-06-15
  • CAS:79-14-1
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 1000kg
  • Glycolic acid
  • Glycolic acid pictures
  • $2500.00 / 250kg
  • 2024-06-14
  • CAS:
  • Min. Order: 1000kg
  • Purity: 70% solution
  • Supply Ability: 4000mt
  • Glycolic acid
  • Glycolic acid pictures
  • $2500.00 / 250kg
  • 2024-06-14
  • CAS:79-14-1
  • Min. Order: 1000kg
  • Purity: 70%
  • Supply Ability: 20000

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  • Glycolic acid is a water-soluble alpha hydroxy acid (AHA) made from sugar cane. It is one of the most widely used AHAs in skin....
  • Mar 9,2022
Glycolic acid Chemical Properties
Melting point 75-80 °C (lit.)
Boiling point 112 °C
density 1.25 g/mL at 25 °C
vapor pressure 10.8 hPa (80 °C)
refractive index n20/D 1.424
Fp 112°C
storage temp. Store below +30°C.
solubility H2O: 0.1 g/mL, clear
form Solution
pka3.83(at 25℃)
color White to off-white
PH2 (50g/l, H2O, 20℃)
Odorat 100.00 %. odorless very mild buttery
Odor Typebuttery
Water Solubility SOLUBLE
Sensitive Hygroscopic
Merck 14,4498
BRN 1209322
Stability:Stable. Incompatible with bases, oxidizing agents and reducing agents.
LogP-1.07 at 20℃
CAS DataBase Reference79-14-1(CAS DataBase Reference)
NIST Chemistry ReferenceAcetic acid, hydroxy-(79-14-1)
EPA Substance Registry SystemGlycolic acid (79-14-1)
Safety Information
Hazard Codes C
Risk Statements 34-22-20
Safety Statements 26-36/37/39-45-23
RIDADR UN 3265 8/PG 3
WGK Germany 1
RTECS MC5250000
HS Code 2918 19 98
HazardClass 8
PackingGroup II
Hazardous Substances Data79-14-1(Hazardous Substances Data)
ToxicityLD50 orally in rats: 1.95 g/kg, H. F. Smyth et al., J. Ind. Hyg. Toxicol. 23, 259 (1941)
MSDS Information
ACROS English
SigmaAldrich English
ALFA English
Glycolic acid Usage And Synthesis
DescriptionGlycolic acid is the smallest alpha-hydroxy acid (AHA). It is mainly supplemented to various skin-care products to improve the skin’s appearance and texture. It can also reduce wrinkles, acne scarring, and hyperpigmentation. In textile industry, it can be used as a dyeing and tanning agent. It can also be used as a flavoring agent in food processing, and as a skin care agent in the pharmaceutical industry. It can also be added into emulsion polymers, solvents and ink additives to improve flow properties and impart gloss. Moreover, it is a useful intermediate for organic synthesis including oxidative-reduction, esterification and long chain polymerization.
ReferencesBhatia, A. C., and F. Jimenez. "Rapid treatment of mild acne with a novel skin care system containing 1% salicylic acid, 10% buffered glycolic acid, and botanical ingredients." Journal of Drugs in Dermatology Jdd13.6(2014):678-83.
Chemical PropertiesGlycolic acid, CH20HCOOH, also known as hydroxyacetic acid, is composed of colorless deliquescent leaflets that decompose at approximately 78° C (172 OF). It is soluble in water,alcohol,and ether.Glycolic acid is used in dyeing, tanning, electropolishing,and in foodstuffs. It is produced by oxidizing glycol with dilute nitric acid.
UsesIn the processing of textiles, leather, and metals; in pH control, and wherever a cheap organic acid is needed, e.g. in the manufacture of adhesives, in copper brightening, decontamination cleaning, dyeing, electroplating, in pickling, cleaning and chemical milling of metals.
Usesglycolic acid (hydroxyacetic acid) reduces corenocyte cohesion and corneum layer thickening where an excess buildup of dead skin cells can be associated with many common skin problems, such as acne, dry and severely dry skin, and wrinkles. glycolic acid acts by dissolving the internal cellular cement responsible for abnormal keratinization, facilitating the sloughing of dead skin cells. It also improves skin hydration by enhancing moisture uptake as well as increasing the skin’s ability to bind water. This occurs in the cellular cement through an activation of glycolic acid and the skin’s own hyaluronic acid content. Hyaluronic acid is known to retain an impressive amount of moisture and this capacity is enhanced by glycolic acid. As a result, the skin’s own ability to raise its moisture content is increased. glycolic acid is the simplest alpha hydroxyacid (AHA). It is also the AHA that scientists and formulators believe has greater penetration potential largely due to its smaller molecular weight. It is mildly irritating to the skin and mucous membranes if the formulation contains a high glycolic acid concentration and/ or a low pH. glycolic acid proves beneficial for acne-prone skin as it helps keep pores clear of excess keratinocytes. It is also used for diminishing the signs of age spots, as well as actinic keratosis. However, glycolic acid is most popularly employed in anti-aging cosmetics because of its hydrating, moisturizing, and skin-normalizing abilities, leading to a reduction in the appearance of fine lines and wrinkles. Regardless of the G skin type, glycolic acid use is associated with softer, smoother, healthier, and younger looking skin. glycolic acid is naturally found in sugarcane but synthetic versions are most often used in cosmetic formulations.
DefinitionChEBI: A 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
PreparationThere are different preparation methods to synthesize glycolic acid. However, the most common method is the catalyzed reaction of formaldehyde with synthesis gas, which costs less. It can be prepared when chloroacetic acid reacts with sodium hydroxide and undergoes re-acidification. Electrolytic reduction of oxalic acid also could synthesize this compound. Glycolic acid can be separated from natural sources like sugarcane, sugar beets, pineapple, cantaloupe, and unripe grapes. It can be prepared by hydrolyzing the cyanohydrin that is derived from formaldehyde.
benefitsGlycolic acid addresses skin issues by exfoliating dead skin cells that accumulate on the surface of the epidermis and contribute to dull, discolored, and uneven looking skin.
Flammability and ExplosibilityNon flammable
Side effectsCommon side effects of Glycolic acid include dry skin, erythema (skin redness), burning sensation, itching, skin irritation, and skin rash. It can make the skin more sensitive in the sunlight, hence always use sunscreen and protective clothing before you step outdoors.
SourceGlycolic acid is widespread in nature and can be separated from natural sources like sugarcane, sugar beets, pineapple, cantaloupe, and unripe grapes.
Purification MethodsCrystallise it from diethyl ether. [Beilstein 3 IV 571.]
Tag:Glycolic acid(79-14-1) Related Product Information
Formic acid Ethanesulfonyl chloride Ethyl glycolate Methyl glycolate Ethylamine hydrochloride Ethylenediaminetetraacetic acid Diethyl acetamidomalonate Ethylenediaminetetraacetic acid disodium salt Citric acid Glycine Ethyl 2-(Chlorosulfonyl)acetate Folic acid Stearic acid 3,4-Dihydroxyphenylacetic acid Ethanol Monoethanolamine Sodium thioglycolate Sodium ethoxide