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| | Amiloride hydrochloride dihydrate Basic information |
| Product Name: | Amiloride hydrochloride dihydrate | | Synonyms: | Modamide;AMILORIDE HCL DIHYDRATE;AMILORIDE HYDROCHLORIDE 2-HYDRATE;Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride, dihydrate;AMILORIDE HYDROCHLORIDE (500 MG);AMILORIDEHYDROCHLORIDE,USP;3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide hydrochloride dihydrate;Amiloride hydrochloride dihydrate | | CAS: | 17440-83-4 | | MF: | C6H8ClN7O.HCl.2H2O | | MW: | 302.12 | | EINECS: | 620-474-8 | | Product Categories: | MK-870 | | Mol File: | 17440-83-4.mol |  |
| | Amiloride hydrochloride dihydrate Chemical Properties |
| Melting point | >240℃ | | RTECS | UQ2275500 | | storage temp. | Store at -20°C | | solubility | Slightly soluble in water and in anhydrous ethanol. | | pka | 8.7(at 25℃) | | Water Solubility | Soluble in water at 50mg/ml |
| WGK Germany | 3 | | HazardClass | 6.1 | | HS Code | 2933995300 |
| | Amiloride hydrochloride dihydrate Usage And Synthesis |
| Chemical Properties | Pale yellow or greenish-yellow powder. | | Uses | An epithelial sodium channel blocker | | Uses | Diuretic;Antialdosteron | | Uses | Amiloride hydrochloride dihydrate is used as a calcium channel and sodium channel protein inhibitor. It reduces electrical potential across tubular epithelium, inhibits angiogenesis and inhibits capillary morphogenesis completely and reversibly at approximately 130 ?M. Amiloride ? HCl is an inhibitor of Sodium/Potassium-ATPase Protein. Defines the I2A-amiloride sensitive and I2B-amiloride insensitive imidazoline binding Blocks TRPP3, acid sensing- (ASIC) and mechanogated membrane-ion channels, as well as the Na+/H+ exchanger. Also inhibits urokinase-type plasminogen activator (uPA); has no effect on tissue-type plasminogen activator. | | Definition | ChEBI: A hydrate that is the dihydrate of amiloride hydrochloride. | | Brand name | Midamor (Merck). |
| | Amiloride hydrochloride dihydrate Preparation Products And Raw materials |
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