PUROMYCINAMINONUCLEOSIDE
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | KG/T |
| Update Time: | 2019-12-20 |
Product Details
| Product Name: PUROMYCINAMINONUCLEOSIDE | CAS No.: 58-60-6 |
| EC-No.: 200-388-3 | Min. Order: 1KG |
| Purity: 99% | Supply Ability: KG/T |
| Release date: 2019/12/20 |
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Product Name:
PUROMYCIN AMINONUCLEOSIDE
Synonyms:
3'-AMINO-3'-DEOXY-N6,N6-DIMETHYLADENOSINE;3'-AMINO-3'-DEOXY-N,N-DIMETHYL-ADENOSINE;6-DIMETHYLAMIN-9-[3'-AMINO-3'DEOXYRIBOSYL]-PURINE;Puromycin Aminonucleoside, 6-Dimethylamin-9-[3-amino-3deoxyribosyl]-purine;9-(3-Amino-3-deoxy-.beta.-D-ribofuranosyl)-N,N-dimethyl-9H-purin-6-amine;Adenosine, 3'-amino-3'-deoxy-N,N-dimethyl-;Aids000507;Aids-000507
CAS:
58-60-6
MF:
C12H18N6O3
MW:
294.31
EINECS:
200-388-3
Product Categories:
-
Mol File:
58-60-6.mol
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PUROMYCIN AMINONUCLEOSIDE Chemical Properties
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Melting point
235℃ (Decomposition)
Boiling point
436.08°C (rough estimate)
density
1.2131 (rough estimate)
refractive index
1.7000 (estimate)
Fp
>110°(230°F)
storage temp.
2-8°C
solubility
H2O: 50 mg/mL, clear, slightly yellow
form
liquid
pka
13.26±0.70(Predicted)
Water Solubility
Soluble in water at 50mg/ml. May require heating
BRN
93902
InChIKey
RYSMHWILUNYBFW-GRIPGOBMSA-N
EPA Substance Registry System
Adenosine, 3'-amino-3'-deoxy-N,N-dimethyl- (58-60-6)
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Chemical Properties
White crystal
Uses
Puromycin aminonucleoside is a semi-synthetic derivative of puromycin which lacks the methoxyphenylalanyl moiety. Puromycin aminonucleoside is the key intermediate in the synthesis of semi-synthetic analogues of puromycin. It does not inhibit protein synthesis or induce apoptosis, but exhibits antitumour properties. Puromycin aminonucleoside-induced nephrosis is a well-described model of human idiopathic nephrotic syndrome, suppressing integrin expression in cultured glomerular epithelial cells.
Uses
Puromycin aminonucleoside is a semi-synthetic derivative of puromycin which lacks the methoxyphenylalanyl moiety. Puromycin aminonucleoside is the key intermediate in the synthesis of semi-synthetic analogues of puromycin. It does not inhibit protein synthesis or induce apoptosis, but exhibits antitumor properties. Puromycin aminonucleoside-induced nephrosis is a well-described model of human idiopathic nephrotic syndrome, suppressing integrin expression in cultured glomerular epithelial cells.
Definition
ChEBI: Puromycin derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring.
Safety Profile
An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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