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ChemicalBook >> CAS DataBase List >> (-)-BETA-HYDRASTINE

(-)-BETA-HYDRASTINE

(-)-BETA-HYDRASTINE price.
  • $55 - $1175
  • Product name: (-)-BETA-HYDRASTINE
  • CAS: 118-08-1
  • MF: C21H21NO6
  • MW: 383.39
  • EINECS:204-233-0
  • MDL Number:MFCD00152561
  • Synonyms:HYDRASTINE, (-)-B-(P) (AHP Verified);HYDRASTINE, (-)-B-(P);Hydrastine (base and/or unspecified salts);(1R,9S)-(-)-β-Hydrastine;(3R)-6,7-Dimethoxy-3-[[(1R)-1,2,3,4-tetrahydro-2-methyl-6,7-(methylenedioxy)isoquinoline]-1-yl]isobenzofuran-1(3H)-one;[R,(-)]-6,7-Dimethoxy-3-[[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinoline]-5-yl]isobenzofuran-1(3H)-one;(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone;[S,(-)]-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]isobenzofuran-1(3H)-one
Price14 Properties Safety Information Description
14 prices
Selected condition：
Brand
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 5g
  • ManufacturerAHH
  • Product numberMT-52735
  • Product descriptionHydrastine 98%
  • Packaging5g
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6606AF
  • Product descriptionHydrastine
  • Packaging10mg
  • Price$241
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPXT0001683
  • Product descriptionHYDRASTINE 98.00%
  • Packaging10MG
  • Price$716.1
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS348789
  • Product descriptionHydrastine
  • Packaging10mg
  • Price$378
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611709
  • Product descriptionHydrastine
  • Packaging10mg
  • Price$248.2
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22363
  • Product description(1R,9S)-(–)-β-Hydrastine ≥98%
  • Packaging5mg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22363
  • Product description(1R,9S)-(–)-β-Hydrastine ≥98%
  • Packaging10mg
  • Price$130
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22363
  • Product description(1R,9S)-(–)-β-Hydrastine ≥98%
  • Packaging25mg
  • Price$235
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22363
  • Product description(1R,9S)-(–)-β-Hydrastine ≥98%
  • Packaging50mg
  • Price$401
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004394
  • Product descriptionHydrastine 98+%
  • Packaging5mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004394
  • Product descriptionHydrastine 98+%
  • Packaging10mg
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC23931
  • Product descriptionHydrastine >98%
  • Packaging10mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number1313210
  • Product description(1R,9S)-(?)-β-Hydrastine United States Pharmacopeia (USP) Reference Standard
  • Packaging10mg
  • Price$644
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberH675701
  • Product description(-)-β-Hydrastine
  • Packaging50mg
  • Price$1175
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-52735 Hydrastine 98% 5g $230 2021-12-16 Buy
AK Scientific 6606AF Hydrastine 10mg $241 2021-12-16 Buy
American Custom Chemicals Corporation PXT0001683 HYDRASTINE 98.00% 10MG $716.1 2021-12-16 Buy
Arctom AS348789 Hydrastine 10mg $378 2021-12-16 Buy
Biorbyt Ltd orb611709 Hydrastine 10mg $248.2 2021-12-16 Buy
Cayman Chemical 22363 (1R,9S)-(–)-β-Hydrastine ≥98% 5mg $68 2024-03-01 Buy
Cayman Chemical 22363 (1R,9S)-(–)-β-Hydrastine ≥98% 10mg $130 2024-03-01 Buy
Cayman Chemical 22363 (1R,9S)-(–)-β-Hydrastine ≥98% 25mg $235 2024-03-01 Buy
Cayman Chemical 22363 (1R,9S)-(–)-β-Hydrastine ≥98% 50mg $401 2024-03-01 Buy
Crysdot CD31004394 Hydrastine 98+% 5mg $55 2021-12-16 Buy
Crysdot CD31004394 Hydrastine 98+% 10mg $76 2021-12-16 Buy
DC Chemicals DC23931 Hydrastine >98% 10mg $88 2021-12-16 Buy
Sigma-Aldrich 1313210 (1R,9S)-(?)-β-Hydrastine United States Pharmacopeia (USP) Reference Standard 10mg $644 2024-03-01 Buy
TRC H675701 (-)-β-Hydrastine 50mg $1175 2021-12-16 Buy

Properties

Melting point :132℃
alpha :D20 -50° (c = 0.3 in abs alc)
Boiling point :510.32°C (rough estimate)
Density :1.339±0.06 g/cm3 (20 ºC 760 Torr)
refractive index :1.5614 (estimate)
storage temp. :−20°C
solubility :DMF: 10 mg/ml; DMSO: 10 mg/ml
form :A crystalline solid
pka :7.8(at 25℃)
Water Solubility :30mg/L(20 ºC)
CAS DataBase Reference :118-08-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

(1R,9S)-(–)-β-Hydrastine is an enantiomer of the alkaloid hydrastine that inhibits dopamine biosynthesis (IC50 = 20.7 μM in PC12 cells) by inhibiting tyrosine hydroxylase activity. It inhibits dopamine release with an IC50 value of 66.5 μM in the presence of high extracellular K+ levels. It also inhibits L-type and caffeine-activated store-operated Ca2+ channels and prevents Ca2+ leakage from intracellular stores.

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