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ChemicalBook >> CAS DataBase List >> COMPOUND 401

COMPOUND 401

COMPOUND 401 price.
  • $8 - $1600
  • Product name: COMPOUND 401
  • CAS: 168425-64-7
  • MF: C16H15N3O2
  • MW: 281.31
  • EINECS:
  • MDL Number:MFCD10568147
  • Synonyms:2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one;4H-PyriMido[2,1-a]isoquinolin-4-one, 2-(4-Morpholinyl)-;2-(Morpholin-4-yl)pyrimido[2,1-a]isoquinolin-4-one;2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one;Compound 401, >=98%;2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one;CS-315;COMPOUND401;COMPOUND-401
Price56 Properties Safety Information Description
56 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 5mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mg
  • 10mM*1mLinDMSO
  • 25mg
  • 50mg
  • 100.00mg
  • 100mg
  • 250.00mg
  • 250mg
  • 1G
  • 1.00g
  • 5G
  • Manufactureraablocks
  • Product numberAA001XYY
  • Product descriptionCompound 401 98%
  • Packaging1mg
  • Price$8
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001XYY
  • Product descriptionCompound 401 ≥98%(HPLC)
  • Packaging5mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001XYY
  • Product descriptionCompound 401 ≥98%(HPLC)
  • Packaging10mg
  • Price$11
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001XYY
  • Product descriptionCompound 401 ≥98%(HPLC)
  • Packaging25mg
  • Price$18
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001XYY
  • Product descriptionCompound 401 98%
  • Packaging50mg
  • Price$32
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001XYY
  • Product descriptionCompound 401 ≥98%(HPLC)
  • Packaging100mg
  • Price$58
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS89817
  • Product description2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one 95%
  • Packaging1G
  • Price$300
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS89817
  • Product description2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one 95%
  • Packaging5G
  • Price$1200
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number5139CR
  • Product description2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
  • Packaging25mg
  • Price$479
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number5139CR
  • Product description2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA279135
  • Product descriptionCompound401 98+%
  • Packaging250mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA279135
  • Product descriptionCompound401 98+%
  • Packaging100mg
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA279135
  • Product descriptionCompound401 98+%
  • Packaging25mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA279135
  • Product descriptionCompound401 98+%
  • Packaging50mg
  • Price$52
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA279135
  • Product descriptionCompound401 98+%
  • Packaging5mg
  • Price$24
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA279135
  • Product descriptionCompound401 98+%
  • Packaging10mg
  • Price$31
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001XYY Compound 401 98% 1mg $8 2026-05-28 Buy
aablocks AA001XYY Compound 401 ≥98%(HPLC) 5mg $10 2026-05-28 Buy
aablocks AA001XYY Compound 401 ≥98%(HPLC) 10mg $11 2026-05-28 Buy
aablocks AA001XYY Compound 401 ≥98%(HPLC) 25mg $18 2026-05-28 Buy
aablocks AA001XYY Compound 401 98% 50mg $32 2026-05-28 Buy
aablocks AA001XYY Compound 401 ≥98%(HPLC) 100mg $58 2026-05-28 Buy
ACHEMBLOCK S89817 2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one 95% 1G $300 2026-05-27 Buy
ACHEMBLOCK S89817 2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one 95% 5G $1200 2026-05-27 Buy
AK Scientific 5139CR 2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one 25mg $479 2021-12-16 Buy
AK Scientific 5139CR 2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one 1mg $133 2021-12-16 Buy
Ambeed A279135 Compound401 98+% 250mg $132 2021-12-16 Buy
Ambeed A279135 Compound401 98+% 100mg $67 2021-12-16 Buy
Ambeed A279135 Compound401 98+% 25mg $40 2021-12-16 Buy
Ambeed A279135 Compound401 98+% 50mg $52 2021-12-16 Buy
Ambeed A279135 Compound401 98+% 5mg $24 2021-12-16 Buy
Ambeed A279135 Compound401 98+% 10mg $31 2021-12-16 Buy
Next Last

Properties

Melting point :184-186℃ (ethanol )
Boiling point :456.9±55.0 °C(Predicted)
Density :1.36±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. :Store at RT
solubility :DMSO : 6 mg/mL (21.33 mM; Need ultrasonic and warming)
pka :1.01±0.20(Predicted)
form :powder to crystal
color :White to Light yellow
InChI :1S/C16H15N3O2/c20-15-11-14(18-7-9-21-10-8-18)17-16-13-4-2-1-3-12(13)5-6-19(15)16/h1-6,11H,7-10H2
InChIKey :BVRDQVRQVGRNHG-UHFFFAOYSA-N
CAS DataBase Reference :168425-64-7

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Compound 401 is a cell-permeable pyrimido-isoquinolinone compound that acts as a potent, reversible, and ATP-competitive inhibitor of DNA-PK (IC50 = 280 nM) with ~19-fold selectivity over mTOR (FRAP) (IC50 = 5.3 μM). Compound 401 exhibits much reduced or no activity against 43 other commonly studied kinases, including PI 3-K, ATM, and ATR. Compound 401 has been shown to induce apoptosis and inhibit FRAP-dependent growth in TSC1-/- murine embryo fibroblasts.

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. 3B Pharmachem (Wuhan) International Co.,Ltd. TCI (Shanghai) Development Co., Ltd. Hangzhou Sage Chemical Co., Ltd. Haoyuan Chemexpress Co., Ltd. TOKYO CHEMICAL INDUSTRY CO., LTD. TCI Europe TCI AMERICA MedChemexpress LLC AdooQ BioScience, LLC