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ChemicalBook >> CAS DataBase List >> β-Estradiol

β-Estradiol

β-Estradiol price.
  • $15 - $3810
  • Product name: β-Estradiol
  • CAS: 50-28-2
  • MF: C18H24O2
  • MW: 272.39
  • EINECS:200-023-8
  • MDL Number:MFCD01074033
  • Synonyms:Cimara;Estradot;Estring;á-estradiol;ESTRADIOL,MICRONIZEDPOWDER,USP;Estradiol Base Benzoate & derivatives;Estradiol Solution, 100ppm;17β-Estradiol solution
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  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
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  • DC Chemicals
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  • Matrix Scientific
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  • ManufacturerAK Scientific
  • Product numberJ93754
  • Product descriptionEstradiol
  • Packaging25g
  • Price$130
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberL03801
  • Product descriptionbeta-Estradiol, 99% (dry wt.), ca 3% water
  • Packaging1g
  • Price$45.8
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberL03801
  • Product descriptionbeta-Estradiol, 99% (dry wt.), ca 3% water
  • Packaging5g
  • Price$149
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberL03801
  • Product descriptionbeta-Estradiol, 99% (dry wt.), ca 3% water
  • Packaging25g
  • Price$531.65
  • Updated2024-03-01
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  • ManufacturerApexBio Technology
  • Product numberA8425
  • Product descriptionEstradiol
  • Packaging1g
  • Price$52
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberCFN90035
  • Product descriptionbeta-Estradiol
  • Packaging20mg
  • Price$40
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb593460
  • Product descriptionβ-ESTRADIOL
  • Packaging50μg
  • Price$425
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb134505
  • Product descriptionβ-ESTRADIOL >99%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb593460
  • Product descriptionβ-ESTRADIOL
  • Packaging100μg
  • Price$635.8
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb134505
  • Product descriptionβ-ESTRADIOL >99%
  • Packaging250mg
  • Price$765
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb593460
  • Product descriptionβ-ESTRADIOL
  • Packaging500μg
  • Price$957.1
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb134505
  • Product descriptionβ-ESTRADIOL >99%
  • Packaging1g
  • Price$1504.5
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFE10880
  • Product descriptionb-Estradiol
  • Packaging5G
  • Price$63
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFE10880
  • Product descriptionb-Estradiol
  • Packaging10g
  • Price$105
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFE10880
  • Product descriptionb-Estradiol
  • Packaging25g
  • Price$236.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFE10880
  • Product descriptionb-Estradiol
  • Packaging50g
  • Price$420
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J93754 Estradiol 25g $130 2021-12-16 Buy
Alfa Aesar L03801 beta-Estradiol, 99% (dry wt.), ca 3% water 1g $45.8 2024-03-01 Buy
Alfa Aesar L03801 beta-Estradiol, 99% (dry wt.), ca 3% water 5g $149 2024-03-01 Buy
Alfa Aesar L03801 beta-Estradiol, 99% (dry wt.), ca 3% water 25g $531.65 2024-03-01 Buy
ApexBio Technology A8425 Estradiol 1g $52 2021-12-16 Buy
Arctom CFN90035 beta-Estradiol 20mg $40 2021-12-16 Buy
Biorbyt Ltd orb593460 β-ESTRADIOL 50μg $425 2021-12-16 Buy
Biorbyt Ltd orb134505 β-ESTRADIOL >99% 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb593460 β-ESTRADIOL 100μg $635.8 2021-12-16 Buy
Biorbyt Ltd orb134505 β-ESTRADIOL >99% 250mg $765 2021-12-16 Buy
Biorbyt Ltd orb593460 β-ESTRADIOL 500μg $957.1 2021-12-16 Buy
Biorbyt Ltd orb134505 β-ESTRADIOL >99% 1g $1504.5 2021-12-16 Buy
Biosynth Carbosynth FE10880 b-Estradiol 5G $63 2021-12-16 Buy
Biosynth Carbosynth FE10880 b-Estradiol 10g $105 2021-12-16 Buy
Biosynth Carbosynth FE10880 b-Estradiol 25g $236.5 2021-12-16 Buy
Biosynth Carbosynth FE10880 b-Estradiol 50g $420 2021-12-16 Buy

Properties

Melting point :178-179 °C(lit.)
alpha :D25 +76 to +83° (dioxane)
Boiling point :355.44°C (rough estimate)
Density :1.0708 (rough estimate)
refractive index :80.4 ° (C=1, Dioxane)
Flash point :2℃
storage temp. :room temp
solubility :Practically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent), slightly soluble in methylene chloride.
pka :pKa 10.71±0.02(H2O(0.1% p-dioxane) t=25±0.1 I=0.03(KCl))(Approximate)
form :powder
color :White to off-white
Water Solubility :Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils.
Merck :14,3703
BRN :1914275
BCS Class :1
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :VOXZDWNPVJITMN-ZBRFXRBCSA-N
CAS DataBase Reference :50-28-2(CAS DataBase Reference)
NIST Chemistry Reference :Estra-1,3,5(10)-triene-3,17beta-diol(50-28-2)
EPA Substance Registry System :Estradiol (50-28-2)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H362 May cause harm to breast-fed children Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy/while nursing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P273 Avoid release to the environment.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

β-Estradiol is the major estrogen secreted by the premenopausal ovary. It acts as an estrogenic hormone receptor (ER) agonist and activator of PI 3-kinase. Further, it is used in the treatment of infertility in women, prostate cancer and breast cancer. It is also employed as an agent of stimulating female puberty induction, as in the treatment of delayed puberty caused by hypogonadism or Turner's syndrome. In addition to this, it is used as part of the hormone replacement therapy for transgender women.

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