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Estradiol

Estradiol Suppliers list
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Email: Abel@chembj.com
Products Intro: Product Name:Estradiol
CAS:50-28-2
Purity:99% Package:11/G
Company Name: Wuhan DKY Technology Co.,Ltd.  Gold
Tel:027-81302011 15347069687
Email:sales@whdky.com;2851686510@qq.com
Products Intro:CAS:50-28-2
Purity:99% Package:1kg,5kg,25kg
Company Name: Wuhan Biocar Bio-Pharm Co., Ltd.  Gold
Tel:86 15387057351
Email:sales@biocar.cn
Products Intro:Product Name:Estradiol
CAS:50-28-2
Purity:99% Package:5g 100g 1kg Remarks:Pharmacopoeial grade
Company Name: 3600Chem  Gold
Tel:027-59207852 51787268 18827367472
Email:sales@3600chem.com
Products Intro:Product Name:β-estradiol
CAS:50-28-2
Purity:99% Package:1g,5g,10g,100g,1kg
Company Name: Wuhan Fortuna Chemical Co., Ltd  Gold
Tel:+86-27-59207852 85767163
Email:info@fortunachem.com
Products Intro:Product Name:β-estradiol
CAS:50-28-2
Purity:USP Package:25kg/fibre drum
Estradiol Basic information
Indications and Usage Adverse reactions Contradictions
Product Name:Estradiol
Synonyms:BETA-ESTRADIOL-16,16,17-D3;17BETA-ESTRADIOL-16,16,17-D3;(+)-3,17β-estradiol;(17b)-estra-1,3,5(10)-triene-3,17diol;(17β)-estra-1,3,5(10)-triene-3,17diol;.alpha.-Oestradiol;.beta.-Oestradiol;17-.beta.-Estra-1,3,5(10)-triene-3,17-diol
CAS:50-28-2
MF:C18H24O2
MW:272.38
EINECS:200-023-8
Product Categories:Steroids;Estrogen;Hormone;Analytical Chemistry;Biochemistry;Environmental Endocrine Disruptors;Estradiol, etc. (Environmental Endocrine Disruptors);Hydroxysteroids;Intracellular receptor;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;API;VIVELLE;Hormone Drugs;Inhibitors
Mol File:50-28-2.mol
Estradiol Structure
Estradiol Chemical Properties
Melting point 178-179 °C(lit.)
refractive index 80.4 ° (C=1, Dioxane)
Fp 2℃
storage temp. 2-8°C
form powder
Water Solubility Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils.
Merck 14,3703
BRN 1914275
Stability:Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference50-28-2(CAS DataBase Reference)
NIST Chemistry ReferenceEstra-1,3,5(10)-triene-3,17beta-diol(50-28-2)
EPA Substance Registry SystemEstra-1,3,5(10)- triene-3,17-diol (17.beta.)-(50-28-2)
Safety Information
Hazard Codes T,Xn,F
Risk Statements 60-61-45-63-64-40-36-20/21/22-11
Safety Statements 53-22-36/37/39-45-36/37-26-16
RIDADR 2811
WGK Germany 3
RTECS KG2975000
8-10
HazardClass 6.1
PackingGroup III
Hazardous Substances Data50-28-2(Hazardous Substances Data)
MSDS Information
ProviderLanguage
1,3,5-Estratriene-3,17beta-diol English
SigmaAldrich English
Estradiol Usage And Synthesis
Indications and UsageEstradiol is a white or milky white ordorless crystalline powder. It is soluble in dioxane and acetone, slightly soluble in ethanol, and insoluble in water.
Estradiol is the intermediate between estradiol valerate and estradiol benzoate, and it is a type of estrogen drug. It can be used to treat uterine functional bleeding, primary amenorrhea, menopausal syndrome, and prostate cancer. Estradiol can promote and adjust the normal growth of female sex organs and secondary sex characteristics, promote mammary duct maturation and growth, and aid in posseting. Estradiol can also be used in biochemical research.
Adverse reactionsIn high dosages, estradiol can inhibit the release of anterior pituitary prolactin, thus decreasing breast milk secretion. However, nausea, vomiting and endometrial hyperplasia-induced bleeding may occur. Patients with liver or kidney failure should use with caution.
ContradictionsDo not use on breasts, vaginal area and vaginal mucosa.
Chemical PropertiesWhite Crystalline Powder
UsesPotent mammalian estrogenic hormone produced by the ovary.
UsesEstradiol is the major estrogen secreted by the premenopausal ovary.
DefinitionChEBI: The 17beta-isomer of estradiol.
Biological ActivityEndogenous estrogen receptor (ER) agonist (K i values are 0.12 and 0.13 nM for ER α and ER β respectively). Also high affinity ligand at membrane estrogen GPR30 receptors.
Tag:Estradiol(50-28-2) Related Product Information
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