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ChemicalBook >> CAS DataBase List >> Vatalanib Dihydrochloride

Vatalanib Dihydrochloride

Vatalanib Dihydrochloride price.
  • $51 - $1758.49
  • Product name: Vatalanib Dihydrochloride
  • CAS: 212141-51-0
  • MF: C20H17Cl3N4
  • MW: 419.74
  • EINECS:
  • MDL Number:MFCD08458964
  • Synonyms:CGP-79787 Dihydrochlorid;N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine Dihydrochloride;Vatalanib Dihydrochloride;CGP-79787 Dihydrochloride;Vatalanib 2hcl((ZK-222584,PTK 787);Vatalanib dihydrochloride (PTK787);CGP-79787;CGP-79787D
33 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Labseeker
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 5MG
  • 10MG
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 2g
  • ManufacturerAK Scientific
  • Product number0818AB
  • Product descriptionN-(4-Chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-aminedihydrochloride
  • Packaging50mg
  • Price$157
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA392716
  • Product descriptionVatalanib dihydrochloride 98+%
  • Packaging50mg
  • Price$214
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA392716
  • Product descriptionVatalanib dihydrochloride 98+%
  • Packaging100mg
  • Price$278
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA392716
  • Product descriptionVatalanib dihydrochloride 98+%
  • Packaging250mg
  • Price$417
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA392716
  • Product descriptionVatalanib dihydrochloride 98+%
  • Packaging1g
  • Price$937
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000275
  • Product descriptionVATALANIB HYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000076
  • Product descriptionCGP-79787 DIHYDROCHLORIDE 95.00%
  • Packaging10MG
  • Price$697.34
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000076
  • Product descriptionCGP-79787 DIHYDROCHLORIDE 95.00%
  • Packaging100MG
  • Price$1758.49
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1778
  • Product descriptionVatalanib(PTK787)2HCl
  • Packaging50mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIFK0044
  • Product descriptionVatalanib,dihydrochloridesalt
  • Packaging10mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIFK0044
  • Product descriptionVatalanib,dihydrochloridesalt
  • Packaging25mg
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIFK0044
  • Product descriptionVatalanib,dihydrochloridesalt
  • Packaging50mg
  • Price$167
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60311
  • Product descriptionVatalanib(PTK787)2HCl ≥98%
  • Packaging20mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFV28674
  • Product descriptionVatalanib dihydrochloride
  • Packaging10mg
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFV28674
  • Product descriptionVatalanib dihydrochloride
  • Packaging100mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14868
  • Product descriptionVatalanib (hydrochloride) ≥98%
  • Packaging10mg
  • Price$51
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0818AB N-(4-Chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-aminedihydrochloride 50mg $157 2021-12-16 Buy
Ambeed A392716 Vatalanib dihydrochloride 98+% 50mg $214 2021-12-16 Buy
Ambeed A392716 Vatalanib dihydrochloride 98+% 100mg $278 2021-12-16 Buy
Ambeed A392716 Vatalanib dihydrochloride 98+% 250mg $417 2021-12-16 Buy
Ambeed A392716 Vatalanib dihydrochloride 98+% 1g $937 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000275 VATALANIB HYDROCHLORIDE 95.00% 5MG $550 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000076 CGP-79787 DIHYDROCHLORIDE 95.00% 10MG $697.34 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000076 CGP-79787 DIHYDROCHLORIDE 95.00% 100MG $1758.49 2021-12-16 Buy
ApexBio Technology A1778 Vatalanib(PTK787)2HCl 50mg $150 2021-12-16 Buy
Apolloscientific BIFK0044 Vatalanib,dihydrochloridesalt 10mg $66 2021-12-16 Buy
Apolloscientific BIFK0044 Vatalanib,dihydrochloridesalt 25mg $124 2021-12-16 Buy
Apolloscientific BIFK0044 Vatalanib,dihydrochloridesalt 50mg $167 2021-12-16 Buy
Arctom CFN60311 Vatalanib(PTK787)2HCl ≥98% 20mg $138 2021-12-16 Buy
Biosynth Carbosynth FV28674 Vatalanib dihydrochloride 10mg $54 2021-12-16 Buy
Biosynth Carbosynth FV28674 Vatalanib dihydrochloride 100mg $119 2021-12-16 Buy
Cayman Chemical 14868 Vatalanib (hydrochloride) ≥98% 10mg $51 2024-03-01 Buy

Properties

Melting point :268-2700C
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 20 mg/ml with warming) or in Water (up to 100 mg/ml)
form :solid
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
CAS DataBase Reference :212141-51-0

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Vatalanib is an antagonist of the VEGF receptors, inhibiting the receptor tyrosine kinase activities of VEGFR1 (Flt1), VEGFR2 (KDR), and VEGFR3 (Flt4) with IC50 values of 77, 37, and 190 nM, respectively. It less potently inhibits PDGF and c-Kit (IC50 = 600 and 700 nM) and has no effect on a large panel of additional kinases. Vatalanib completely blocks retinal neovascularization in oxygen-induced ischemic retinopathy in mice, suggesting its use in diabetic retinopathy and other diseases featuring aberrant vascular development.

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