ZSTK474
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- $16 - $3811.5
- Product name: ZSTK474
- CAS: 475110-96-4
- MF: C19H21F2N7O2
- MW: 417.41
- EINECS:
- MDL Number:MFCD08705334
- Synonyms:2-(DifluoroMethyl)-1-[4,6-di(4-Morpholinyl)-1,3,5-triazin-2-yl]-1H-benziMidazole;1H-BenziMidazole, 2-(difluoroMethyl)-1-(4,6-di-4-Morpholinyl-1,3,5-triazin-2-yl)-;ZSTK474 BASE;ZSTK474/ZSTK-474;2-(difluoromethyl)-1-(4,6-dimorpholino-1,3,5-triazin-2-yl)-1H-benzo[d]imidazole;2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-dimorpholino-1,3,5-triazine ZSTK-474;ZSTK 474 2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-dimorpholino-1,3,5-triazine;ZSTK 474
64 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Matrix Scientific
- Medical Isotopes, Inc.
- TCI Chemical
- TRC
Package
- 100.00mg
- 250mg
- 500mg
- 2g
- 10mM*1mLinDMSO
- 20mg
- 50.00mg
- 250.00mg
- 10g
- 10mM(in1mLDMSO)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 1G
- 5G
- Manufactureraablocks
- Product numberAA00DB53
- Product description2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-bis(morpholino)-1,3,5-triazine 98%
- Packaging1mg
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DB53
- Product description2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-bis(morpholino)-1,3,5-triazine 98%
- Packaging10mg
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DB53
- Product description2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-bis(morpholino)-1,3,5-triazine 98%
- Packaging25mg
- Price$23
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DB53
- Product description2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-bis(morpholino)-1,3,5-triazine 98%
- Packaging50mg
- Price$44
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DB53
- Product description2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-bis(morpholino)-1,3,5-triazine 98%
- Packaging100mg
- Price$72
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DB53
- Product description2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-bis(morpholino)-1,3,5-triazine 98
- Packaging200mg
- Price$135
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberL14966
- Product descriptionZSTK-474 98%
- Packaging1G
- Price$250
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL14966
- Product descriptionZSTK-474 98%
- Packaging5G
- Price$1220
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1099-M050
- Product descriptionZSTK474 ≥95%
- Packaging50mg
- Price$286
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1099-M100
- Product descriptionZSTK474 ≥95%
- Packaging100mg
- Price$427
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1099-M100
- Product descriptionZSTK474 ≥95%
- Packaging100mg
- Price$427
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1099-M005
- Product descriptionZSTK474 ≥95%
- Packaging5mg
- Price$70
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1099-M010
- Product descriptionZSTK474 ≥95%
- Packaging10mg
- Price$76
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1099-M001
- Product descriptionZSTK474 ≥95%
- Packaging1mg
- Price$54
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberX7419
- Product descriptionZSTK474
- Packaging50mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7419
- Product descriptionZSTK474
- Packaging100mg
- Price$114
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00DB53 | 2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-bis(morpholino)-1,3,5-triazine 98% | 1mg | $16 | 2026-05-28 | Buy |
| aablocks | AA00DB53 | 2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-bis(morpholino)-1,3,5-triazine 98% | 10mg | $19 | 2026-05-28 | Buy |
| aablocks | AA00DB53 | 2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-bis(morpholino)-1,3,5-triazine 98% | 25mg | $23 | 2026-05-28 | Buy |
| aablocks | AA00DB53 | 2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-bis(morpholino)-1,3,5-triazine 98% | 50mg | $44 | 2026-05-28 | Buy |
| aablocks | AA00DB53 | 2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-bis(morpholino)-1,3,5-triazine 98% | 100mg | $72 | 2026-05-28 | Buy |
| aablocks | AA00DB53 | 2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-bis(morpholino)-1,3,5-triazine 98 | 200mg | $135 | 2026-05-28 | Buy |
| ACHEMBLOCK | L14966 | ZSTK-474 98% | 1G | $250 | 2026-05-27 | Buy |
| ACHEMBLOCK | L14966 | ZSTK-474 98% | 5G | $1220 | 2026-05-27 | Buy |
| Adipogen Life Sciences | SYN-1099-M050 | ZSTK474 ≥95% | 50mg | $286 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1099-M100 | ZSTK474 ≥95% | 100mg | $427 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1099-M100 | ZSTK474 ≥95% | 100mg | $427 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1099-M005 | ZSTK474 ≥95% | 5mg | $70 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1099-M010 | ZSTK474 ≥95% | 10mg | $76 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1099-M001 | ZSTK474 ≥95% | 1mg | $54 | 2026-05-06 | Buy |
| AK Scientific | X7419 | ZSTK474 | 50mg | $84 | 2021-12-16 | Buy |
| AK Scientific | X7419 | ZSTK474 | 100mg | $114 | 2021-12-16 | Buy |
Properties
Melting point :217-219 °C(Solv: ethanol (64-17-5))
Boiling point :640.3±65.0 °C(Predicted)
Density :1.57
storage temp. :-20°C
solubility :Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 2.5 mg/ml with warming).
form :White powder.
pka :5.21±0.10(Predicted)
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :InChI=1S/C19H21F2N7O2/c20-15(21)16-22-13-3-1-2-4-14(13)28(16)19-24-17(26-5-9-29-10-6-26)23-18(25-19)27-7-11-30-12-8-27/h1-4,15H,5-12H2
InChIKey :HGVNLRPZOWWDKD-UHFFFAOYSA-N
SMILES :C1(C(F)F)N(C2=NC(N3CCOCC3)=NC(N3CCOCC3)=N2)C2=CC=CC=C2N=1
Boiling point :640.3±65.0 °C(Predicted)
Density :1.57
storage temp. :-20°C
solubility :Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 2.5 mg/ml with warming).
form :White powder.
pka :5.21±0.10(Predicted)
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :InChI=1S/C19H21F2N7O2/c20-15(21)16-22-13-3-1-2-4-14(13)28(16)19-24-17(26-5-9-29-10-6-26)23-18(25-19)27-7-11-30-12-8-27/h1-4,15H,5-12H2
InChIKey :HGVNLRPZOWWDKD-UHFFFAOYSA-N
SMILES :C1(C(F)F)N(C2=NC(N3CCOCC3)=NC(N3CCOCC3)=N2)C2=CC=CC=C2N=1
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||||||
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Description
ZSTK474 is a triazine derivative that acts as an inhibitor of class I phosphatidylinositol 3-kinase (PI3K) isoforms (IC50s = 17, 53, and 6 nM for p110β, -γ, and -δ, respectively). It is selective for PI3K, as it has negligible activity against 139 other kinases when tested at 30 μM. ZSTK474 is orally bioavailable and shows strong antitumor activity against human cancer xenografts in mice. The efficacy of ZSTK474 against certain cancer cells and tumors can be enhanced by combination therapy.More related product prices
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