N-[Bis(methylsulfanyl)methylidene]-4-chlorobenzene-1-sulfonamide synthesis
- Product Name:N-[Bis(methylsulfanyl)methylidene]-4-chlorobenzene-1-sulfonamide
- CAS Number:13068-12-7
- Molecular formula:C9H10ClNO2S3
- Molecular Weight:295.83
75-15-0
274 suppliers
$40.00/100g
98-64-6
190 suppliers
$10.00/5g
74-88-4
357 suppliers
$15.00/10g
13068-12-7
7 suppliers
$352.00/500mg
Yield:13068-12-7 61%
Reaction Conditions:
Stage #1: carbon disulfide;4-Chlorobenzenesulfonamidewith potassium hydroxide in water;N,N-dimethyl-formamide;Inert atmosphere;Cooling with ice;
Stage #2: methyl iodide in water;N,N-dimethyl-formamide at 10 - 20;Inert atmosphere;
References:
Van Loevezijn, Arnold;Venhorst, Jennifer;Iwema Bakker, Wouter I.;De Korte, Cor G.;De Looff, Wouter;Verhoog, Stefan;Van Wees, Jan-Willem;Van Hoeve, Martijn;Van De Woestijne, Rob P.;Van Der Neut, Martina A. W.;Borst, Alice J. M.;Van Dongen, Maria J. P.;De Bruin, Natasja M. W. J.;Keizer, Hiskias G.;Kruse, Chris G. [Journal of Medicinal Chemistry,2011,vol. 54,# 20,p. 7030 - 7054] Location in patent:supporting information; experimental part
75-15-0
274 suppliers
$40.00/100g
98-64-6
190 suppliers
$10.00/5g
77-78-1
319 suppliers
$22.00/25g
13068-12-7
7 suppliers
$352.00/500mg
98-64-6
190 suppliers
$10.00/5g
13068-12-7
7 suppliers
$352.00/500mg