4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)CHLOROBENZENE synthesis
- Product Name:4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)CHLOROBENZENE
- CAS Number:195062-61-4
- Molecular formula:C12H16BClO2
- Molecular Weight:238.52
76-09-5
401 suppliers
$8.19/250mg
1679-18-1
624 suppliers
$10.00/1g
195062-61-4
138 suppliers
$8.00/1g
Yield: 92%
Reaction Conditions:
with magnesium sulfate in diethyl ether at 20; for 16 h;Inert atmosphere;Schlenk technique;
Steps:
Synthesis of Pinacol Boronic Esters from Boronic Acids; General Procedure (GP1)
General procedure: A mixture of boronic acid (1.0 equiv), pinacol (1.0 equiv) and anhydrous MgSO4 (4.0 equiv) in Et2O (0.5 M) was stirred at r.t. for 16 h. The reaction mixture was filtered and the solvent removed in vacuo. The crude material was purified by distillation or flash column chromatography to give the pure boronic ester.
References:
Casoni, Giorgia;Myers, Eddie L.;Aggarwal, Varinder K. [Synthesis,2016,vol. 48,# 19,art. no. SS-2016-C0356-OP,p. 3241 - 3253]
637-87-6
306 suppliers
$38.00/10 G
73183-34-3
590 suppliers
$6.00/5g
195062-61-4
138 suppliers
$8.00/1g
106-47-8
486 suppliers
$5.00/5 g
73183-34-3
590 suppliers
$6.00/5g
195062-61-4
138 suppliers
$8.00/1g
637-87-6
306 suppliers
$38.00/10 G
![Bis[(pinacolato)boryl]Methane](/CAS/GIF/78782-17-9.gif)
78782-17-9
110 suppliers
$22.00/1g
195062-61-4
138 suppliers
$8.00/1g
106-39-8
476 suppliers
$14.00/5g
73183-34-3
590 suppliers
$6.00/5g
195062-61-4
138 suppliers
$8.00/1g