ChemicalBook CAS DataBase List 2,4-Dichlorophenylacetonitrile

2,4-Dichlorophenylacetonitrile synthesis

10synthesis methods

Product Name:2,4-Dichlorophenylacetonitrile
CAS Number:6306-60-1
Molecular formula:C8H5Cl2N
Molecular Weight:186.04

773837-37-9 Synthesis

773837-37-9
0 suppliers
inquiry

20443-99-6
103 suppliers
$25.00/1g

6306-60-1
246 suppliers
$14.00/5g

Yield:6306-60-1 93%

Reaction Conditions:

in ethanol;water

Steps:

8 Example 8
To a 100 mL round bottom flask was added 2,4-dichlorobenzyl bromide(24 g, 0.1 mol) and ethanol (30 mL) and water (5 mL)Subsequently, sodium cyanide (4.9 g, 0.1 mol) was added and the reaction was stirred. After completion of the reaction, the resulting organic phase was separated and distilled to give 17.30 g of 2,4-dichlorophenylacetonitrile in 93% yield.

References:

Zhejiang Yongtai Pharmaceutical Co., Ltd.;Jin Yizhong;He Renbao;Zhou Guobin;Xie Jianren CN106117028, 2016, A Location in patent:Paragraph 0059; 0060

FullText

773837-37-9 Synthesis

773837-37-9
0 suppliers
inquiry

94-99-5 Synthesis