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2,4-Dichlorophenylacetic acid

CAS No.
19719-28-9
Chemical Name:
2,4-Dichlorophenylacetic acid
Synonyms
DCAA;2-(2,4-dichlorophenyl)acetic acid;2,4-DCPA;2,4-dcaa acid;2.4-Dichloroph;RARECHEM AL BO 0113;TIMTEC-BB SBB003502;LABOTEST-BB LT00454968;Guanfacine Impurity 15;2,4-dcaa acid spike mix
CBNumber:
CB2139146
Molecular Formula:
C8H6Cl2O2
Molecular Weight:
205.04
MDL Number:
MFCD00004318
MOL File:
19719-28-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:55:58

2,4-Dichlorophenylacetic acid Properties

Melting point 129-131 °C (lit.)
Boiling point 294.45°C (rough estimate)
Density 1.3806 (rough estimate)
refractive index 1.5490 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility methanol: 0.1 g/mL, clear
pka 3.92±0.10(Predicted)
form Crystalline Powder
color White to pale yellow-beige
Water Solubility SOLUBLE IN HOT WATER
BRN 1948767
InChI 1S/C8H6Cl2O2/c9-6-2-1-5(3-8(11)12)7(10)4-6/h1-2,4H,3H2,(H,11,12)
InChIKey GXMWLJKTGBZMBH-UHFFFAOYSA-N
SMILES OC(=O)Cc1ccc(Cl)cc1Cl
LogP -0.3-2.8 at 23℃ and pH2-7
CAS DataBase Reference 19719-28-9(CAS DataBase Reference)
FDA UNII 15N730ND47
NIST Chemistry Reference 2,4-Dichlorophenylacetic acid(19719-28-9)
EPA Substance Registry System 2,4-Dichlorophenylacetic acid (19719-28-9)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38-67
Safety Statements  26-36-37/39
WGK Germany  3
HS Code  29163990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
REACH Registrations Inactive
NFPA 704
0
2 0

2,4-Dichlorophenylacetic acid price More Price(69)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 259233 2,4-Dichlorophenylacetic acid 99% 19719-28-9 10g $51.8 2026-04-30 Buy
Sigma-Aldrich 259233 2,4-Dichlorophenylacetic acid 99% 19719-28-9 50g $180 2023-06-20 Buy
TCI Chemical D1812 2,4-Dichlorophenylacetic Acid >98.0%(T) 19719-28-9 25g $23 2026-04-30 Buy
Usbiological 273546 2,4-Dichlorophenylacetic acid Asreported 19719-28-9 50g $213 2026-06-03 Buy
Usbiological 273546 2,4-Dichlorophenylacetic acid Asreported 19719-28-9 100g $315 2026-06-03 Buy
Product number Packaging Price Buy
259233 10g $51.8 Buy
259233 50g $180 Buy
D1812 25g $23 Buy
273546 50g $213 Buy
273546 100g $315 Buy

2,4-Dichlorophenylacetic acid Chemical Properties, Uses, Production

Synthesis

In a 300 ml HC4 autoclave, at 20 bar carbon monoxide pressure and 130°C, a solution of 10 g of 5 g water [278 mmol] and 5 g of N-methylpyrrolidone was added to a solution of 49 g of 2,4-dichlorobenzyl chloride [252.5 mmol] and 18 mg of palladium chloride [0.1 mmol] in 105 g of N-methylpyrrolidone over 1 hour. The pressure was kept constant at 20 bar during the addition. After 16 hours, the mixture was further stirred to constant pressure. After cooling, N-methylpyrrolidone and hydrogen chloride were separated at 150°C and 200 mbar. The residue was added as a melt to water with parallel addition of 50% aqueous sodium hydroxide solution to maintain pH 10. A homogeneous solution was obtained and extracted with 20 ml xylene to remove organic soluble substances. The mixture was then acidified to pH 1 with approximately 30% aqueous hydrochloric acid solution, and 2,4-dichlorophenylacetic acid precipitated as a white solid.

The precipitated product was washed with water until the effluent had a constant pH. The washed product was dried at 100°C under reduced pressure to give 2,4-dichlorophenylacetic acid. Yield: 89%. GC purity: 100%. Melting point: 131-133°C.

Uses

2,4-Dichlorophenylacetic Acid is a useful research chemical.

Chemical Properties

white to pale yellowish-beige crystalline powder

Uses

2,4-Dichlorophenylacetic acid has been used as internal standard in:

  • determination of phenoxyalkanoic acid herbicides in blood by GC with electron-capture detection
  • determination of 2-methyl-4-chlorophenoxyacetic acid (herbicide) in soils by GC technique

Global Suppliers ( 488)
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J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44852 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60

View Latest Price from 2,4-Dichlorophenylacetic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-Dichlorophenylacetic acid pictures 2026-09-30 2,4-Dichlorophenylacetic acid
19719-28-9
$5.00 1KG 99% 200mt/year Jinan Finer Chemical Co., Ltd
2,4-Dichlorophenylacetic acid pictures 2026-09-02 2,4-Dichlorophenylacetic acid
19719-28-9
$5.00 1KG 99% Henan Fengda Chemical Co., Ltd
2,4-Dichlorophenylacetic acid pictures 2026-05-28 2,4-Dichlorophenylacetic acid
19719-28-9
$8.70 10KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
2,4-dcaa acid 2,4-DICHLOROPHENYLACETIC ACID 2,4-DCPA LABOTEST-BB LT00454968 TIMTEC-BB SBB003502 RARECHEM AL BO 0113 Benzeneacetic acid, 2,4-dichloro- 2,4-dcaa acid spike mix 2,4-dichlorophenylacetic acid solution 2,4-Dichlorophenylacetic acid (DCAA) 2,4-Diclorophenyl acetic acid 2,4-Dichlorophenylacetic acid, 98+% 15) 2,4 DICHLORO PHENYL ACETIC ACID 2,4-Dichlorophenylacetic acid 99% 2,4-Dichlorobenzeneacetic acid 2,4-Dichlorophenylacetic acid ,99% 2,4-Dichlorophenylacetic Acid Staandard 4-Dichlorophenylacetic acid 2,4-two chlorobenzeneacetic acid Dichlorophenylacetic aci 2.4-Dichloroph 2,4-dichlorphenylessigsaeure 2,4-Dichlorophenylacetic acid (DCAA) @2.0 μg/mL in MeOH 2,4-DichlorophenylaceticAcid(2,4-DCAA),1000mg/L,1ml 2,4-DichlorophenylaceticAcid> 2,4-Dichlorophenylacetic Acid@1000 μg/mL in MeOH 2,4-DichlorophenylaceticAcid(2,4-DCAA),100mg/L,5x1ml 2,4-Dichlorophenylacetic acid @0.1 mg/mL in Acetone 2,4-Dichlorophenylacetic Acid@100 μg/mL in MeOH 2,4-DichlorophenylaceticAcid(2,4-DCAA),200mg/L,1ml 2,4-DichlorophenylaceticAcid(2,4-DCAA),5000mg/L,1ml 2,4-DichlorophenylaceticAcid(2,4-DCAA),2,000mg/L,1ml 2,4-DichlorophenylaceticAcid(2,4-DCAA),1,000ug/L,1ml 2,4-DichlorophenylaceticAcidSolution(Method8281Surrogate),1,000mg/L,1ml 2,4-Dichlorophenylacetic acid @100 μg/mL in AcCN 2,4-Dichlorophenylacetic acid @1000 μg/mL in Acetone 2,4-DichlorophenylaceticAcid(2,4-DCAA),2,000mg/L,5ml 2,4-Dichlorophenylacetic acid@2.0 μg/mL in Acetone 2,4-DichlorophenylaceticAcid(2,4-DCAA),5000mg/L,10x1ml 2,4-DichlorophenylaceticAcid(2,4-DCAA),100mg/L,1ml 2-(2,4-dichlorophenyl)aceticaci 2,4-dichlorophenacetic acid Guanfacine Impurity 15 2,4-Dichlorophenylacetic acid Solution in Acetone 2,4-Dichlorophenylacetic acid Solution In T-Butylmethyl Ether C12468000 2,4-DichlorophenyLacetiCacid 2-(2,4-dichlorophenyl)acetic acid DCAA 19719-28-9 C8 Carbonyl Compounds Carboxylic Acids Building Blocks Organic Building Blocks Building Blocks Carbonyl Compounds Carboxylic Acids Chemical Synthesis