ChemicalBook CAS DataBase List 2,5-DIBROMOPHENOL

2,5-DIBROMOPHENOL synthesis

5synthesis methods

Product Name:2,5-DIBROMOPHENOL
CAS Number:28165-52-8
Molecular formula:C6H4Br2O
Molecular Weight:251.9

95970-08-4 Synthesis

95970-08-4
97 suppliers
$13.00/1g

38865-40-6
0 suppliers
inquiry

Yield:38865-40-6 53.3%

Reaction Conditions:

with aluminum (III) chloride in N,N-dimethyl-formamide at 80 - 100;

Steps:

2.4 (4) Demethylation reaction:

The product of the third step, 2,5-dibromoanisole 1080 g and DMF 5500 mL, was added to the reaction vessel.Stirring, control temperature was added to 688 g of aluminum trichloride in batches at 80-100 °C. The GC tracks until the reaction is over.After the reaction was completed, dichloroethane and water were added, and the mixture was separated.The oil phase was washed with water and separated, and the obtained oil phase was desolvated to obtain a black solid 2,5-dibromophenol 548 g, a content of 98%, and a yield of 53.3%.

References:

CN109320403,2019,A Location in patent:Paragraph 0011; 0015; 0016; 0020

3638-73-1 Synthesis