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2-Methoxy-4-nitroaniline

2-Methoxy-4-nitroaniline Structure
2-Methoxy-4-nitroaniline structure
CAS No.
97-52-9
Chemical Name:
2-Methoxy-4-nitroaniline
Synonyms
FAST RED B BASE;FAST RED B;RED B BASE;2-AMINO-5-NITROANISOLE;RED B ASE;METHOXY-4-NITROANILINE;4-NITRO-ORTHO-ANISIDINE;AZOIC DIAZO COMPONENT 5;4-NITRO-2-METHOXYANILINE;2-Methoxy-4-nitrobenzenamine
CBNumber:
CB1693973
Molecular Formula:
C7H8N2O3
Molecular Weight:
168.15
MDL Number:
MFCD00007363
MOL File:
97-52-9.mol
MSDS File:
SDS
Last updated:2023-09-21 10:07:12
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2-Methoxy-4-nitroaniline Properties

Melting point 140-142 °C(lit.)
Boiling point 337.07°C (rough estimate)
Density 1,211 g/cm3
refractive index 1.6010 (estimate)
storage temp. Store below +30°C.
solubility 0.2g/l
pka 1.02±0.10(Predicted)
form Crystalline Powder
color Yellow to orange
PH 6.2 (0.2g/l, H2O, 20℃)
Water Solubility slightly soluble
BRN 879619
InChIKey GVBHRNIWBGTNQA-UHFFFAOYSA-N
CAS DataBase Reference 97-52-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII DPU26P1846
NIST Chemistry Reference Benzenamine, 2-methoxy-4-nitro-(97-52-9)
EPA Substance Registry System 2-Methoxy-4-nitroaniline (97-52-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08,GHS09
Signal word  Warning
Hazard statements  H302-H351-H411
Precautionary statements  P202-P264-P270-P273-P301+P312-P308+P313
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-20/21/22
Safety Statements  26-37/39-36/37
RIDADR  UN 3077 9 / PGIII
WGK Germany  2
RTECS  BZ7170000
Hazard Note  Irritant
TSCA  Yes
HS Code  29222900
NFPA 704
0
2 0

2-Methoxy-4-nitroaniline price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 112631 2-Methoxy-4-nitroaniline 98% 97-52-9 100g $60.2 2024-03-01 Buy
TCI Chemical M0118 2-Methoxy-4-nitroaniline >99.0%(GC) 97-52-9 25g $18 2024-03-01 Buy
TCI Chemical M0118 2-Methoxy-4-nitroaniline >99.0%(GC) 97-52-9 500g $193 2024-03-01 Buy
Alfa Aesar B24220 2-Methoxy-4-nitroaniline, 99% 97-52-9 25g $18.65 2024-03-01 Buy
Alfa Aesar B24220 2-Methoxy-4-nitroaniline, 99% 97-52-9 100g $32.65 2024-03-01 Buy
Product number Packaging Price Buy
112631 100g $60.2 Buy
M0118 25g $18 Buy
M0118 500g $193 Buy
B24220 25g $18.65 Buy
B24220 100g $32.65 Buy

2-Methoxy-4-nitroaniline Chemical Properties,Uses,Production

Chemical Properties

2-Methoxy-4-nitroaniline is a yellow to orange crystalline powder. 2-Methoxy-4-nitroaniline (MONA) is a potential nonlinear optical (NLO) material, the N12–O19 bond length of MONA molecule is essentially controlled by the p-character of these hybrid orbitals and also by the nature of the N12–O19 bond. The molecular geometry of the compound is almost planar with the substituents[1].

Uses

2-Methoxy-4-nitroaniline is an important intermediate for preparing organic pigments and color bases of ice dyeing dyestuff. As a benzene dye intermediate, It is generally employed to prepare not only fast pigments but also as a printing and dyeing developer for cotton fabrics. In particular, 2-methoxy-4-nitroaniline is also important in production of some antineoplastic drugs[2-3].

Uses

2-Methoxy-4-nitroaniline is used as a photometric reagent for the determination of ethinylestradiol (ETE), a semi-synthetic estrogen that is widely used in oral contraceptives.

General Description

2-Methoxy-4-nitroaniline is an important inducer of CYP1A2 owing to its small molecular size.

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

The metabolism of 2-methoxy-4-nitroaniline (MNA) occurs via the hydroxylation of the phenyl ring to form 6-hydroxy MNA in Harlan Sprague Dawley rats and B6C3F(1)/N mice.

Solubility in organics

The change trend of the solubility magnitude in different monosolvents from high to low was as follows: N-methylpyrrolidone (NMP) > dimethyl sulfoxide (DMSO) > 1,4-dioxane > ethyl acetate > acetonitrile > ethanol > methanol > n-propanol > isopropanol >  ethylene glycol (EG) > n-butanol > water[2].

References

[1] Bao Y, et al. 2-Methoxy-4-nitroaniline Solubility in Several Monosolvents: Measurement, Correlation, and Solvent Effect Analysis. Journal of Chemical & Engineering Data, 2020; 65: 757–765.
[2] Degawa M, et al.2-Methoxy-4-nitroaniline is a selective inducer of cytochrome P450IA2 (CYP1A2) in rat liver. Cancer Letters, 1995; 96: 95-98.
[3] Ravikumar C, et al. Electronic absorption and vibrational spectra and nonlinear optical properties of 4-methoxy-2-nitroaniline. Physical Chemistry Chemical Physics, 2010; 12: 9452-9460.

2-Methoxy-4-nitroaniline synthesis

93-27-6
97-52-9
Synthesis of 2-Methoxy-4-nitroaniline from N-(2-METHOXY-4-NITROPHENYL)ACETAMIDE

2-Methoxy-4-nitroaniline Preparation Products And Raw materials

Raw materials

o-Anisidine dilute sulphuric acid P-toluenesulfonyl chloride Nitrification Tosyl chloride
PARA TOLUENE Nitric acid Acetic acid N-(2-Methoxyphenyl)acetamide

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Preparation Products

4-Fluoro-3-methoxyaniline C.I.Pigment Yellow 98 5-CHLORO-2-NITROANISOLE 8-METHOXYQUINOLIN-6-AMINE 2-Chloro-5-aminophenol
Pigment Yellow 74 2-METHOXY-4-NITROBENZALDEHYDE 2,5-DIBROMOANISOLE Benzoic acid, 2-[[1-amino-7-[[4-[[6-amino-5-[(3-carboxy-4-hydroxyphenyl)azo]-1-hydroxy-3-sulfo-2-naphthalenyl]azo]-2-methoxyphenyl]azo]-8-hydroxy-3,6-disulfo-2-naphthalenyl]azo]-5-[[6-amino-5-[(3-carboxy-4-hydroxyphenyl)azo]-1-hydroxy-3-sul sodium 4-hydroxy-5-[(2-methoxy-4-nitrophenyl)azo]-6-(phenylamino)naphthalene-2-sulphonate
2,2'-[[4-[(4-Amino-2-methoxyphenyl)azo]-3-methylphenyl]imino]bisethanol Solvent Red 13 Copper, diazotized 2-methoxy-4-nitrobenzenamine-4-[(8-hydroxy-6-sulfo-2-naphthalenyl)amino]benzoic acid coupling products complexes 4-[(2-methoxy-4-nitrophenyl)azo]-N,N-dimethyl-Benzenamine

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2-Methoxy-4-nitroaniline Suppliers

Global( 290)Suppliers
Supplier Tel Email Country ProdList Advantage
Taizhou Suze Chemical Materials Co.,Ltd.
+86-0523-86392777 +86-19825580222 nick.miao@suzechem.com China 23 58
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12456 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Anhui Royal Chemical Co., Ltd. 		+86-25-86655873 +8613962173137 marketing@royal-chem.com China 142 55
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2989 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Jinan Finer Chemical Co., Ltd 		+86-531-88989536 +86-15508631887 sales@finerchem.com China 2967 58
Supplier Advantage
Taizhou Suze Chemical Materials Co.,Ltd.
58
Hebei Mojin Biotechnology Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Anhui Royal Chemical Co., Ltd. 		55
Hefei TNJ Chemical Industry Co.,Ltd. 		55
career henan chemical co 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Jinan Finer Chemical Co., Ltd 		58

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View Lastest Price from 2-Methoxy-4-nitroaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Methoxy-4-nitroaniline pictures 2023-08-26 2-Methoxy-4-nitroaniline
97-52-9
 US $100.00 / KG 1KG 99% 5000KG Hebei Mojin Biotechnology Co., Ltd
2-Methoxy-4-nitroaniline pictures 2022-11-22 2-Methoxy-4-nitroaniline
97-52-9
 US $0.00 / kg 1kg 97.7% 24 tons Taizhou Suze Chemical Materials Co.,Ltd.
2-Methoxy-4-nitroaniline pictures 2022-05-12 2-Methoxy-4-nitroaniline
97-52-9
 US $0.00 / g 10g 99.0% 10tons Wuhan Godbullraw Chemical Co.,ltd

2-Methoxy-4-nitroaniline Spectrum

2-Methoxy-4-nitroaniline(97-52-9)MS2-Methoxy-4-nitroaniline(97-52-9)1HNMR2-Methoxy-4-nitroaniline(97-52-9)13CNMR2-Methoxy-4-nitroaniline(97-52-9)IR12-Methoxy-4-nitroaniline(97-52-9)IR22-Methoxy-4-nitroaniline(97-52-9)Raman

97-52-9(2-Methoxy-4-nitroaniline)Related Search:

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2-Methyl-4-nitroaniline p-Anisidine 3-Amino-4-methoxybenzanilide 4-Methyl-2-nitroaniline NITROGEN DIOXIDE
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redbasecibav redbaseirgav Brilliant Red Developing Base 4B -Amino-5-nitrophenyl methyl ether RED R BASE 4-Nitro-o-anisidine (NH2=1) Benzenamine, 2-methoxy-4-nitro- 4-NITRO-2-ANISIDINE ( 2-METHOXY-4-NITRO ANILINE ) 5-NITRO-2-AMINOANISOLE 5-NITRO-2-ANISIDINE 4-NITRO-O-ANISIDINE 1-AMINO-2-METHOXY-4-NITROBENZENE 2-Amino-5-nitroanis01 2-METHOXY-4-NITROANILINE 2-methoxy-4-nitro-benzenamin 2-methoxy-4-nitro-Benzenamine Amarthol fast red b base amartholfastredbbase naphthanilredbbase Naphthoelan red B base naphthoelanredbbase Naphtoelan red b base Nuclear fast red B salt o-Anisidine, 4-nitro- p-Nitro-o-anisidine Pnoa Red base ciba v Red base irga v Red base nb RedbaseB 3-Nitro-6-aminoanisole 4-Amino-3-methoxynitrobenzene 4-Nitro-6-methoxyaniline 4-nitro-o-anisidin redbasenb Sanyo fast red b base sanyofastredbbase Shinnippon fast red b base shinnipponfastredbbase Showa fast red b base showafastredbbase Symulon red b base symulonredbbase 2-Methoxy-4-nitroani 2-Methoxy-4-nitroaniline, 99% 100GR 2-Methoxy-4-nitroaniline (Fast Red B) illiant Red Developing Base 4B diabaseredb Diazo fast red b diazofastredb Fast red 5na base Fast Red B-T Base fastred5nabase Hiltonil fast red b base hiltonilfastredbbase Kako red b base kakoredbbase Kayaku red b base