2-Bromomethyl-1,3-dioxolane synthesis
- Product Name:2-Bromomethyl-1,3-dioxolane
- CAS Number:4360-63-8
- Molecular formula:C4H7BrO2
- Molecular Weight:167
107-21-1
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75-07-0
425 suppliers
$14.00/5mL
4360-63-8
313 suppliers
$5.00/5g
Yield:4360-63-8 79.2%
Reaction Conditions:
Stage #1:ethylene glycol;acetaldehyde at 20; for 0.5 h;Large scale;
Stage #2: with bromine at 0 - 3; for 3.5 h;Large scale;Temperature;
Steps:
1.b b. Preparation of bromoacetaldehyde ethylene glycol
To a reaction vessel, 10.326kg (166.3mol) of ethylene glycol was added with 3.66 Kg (83.185mol) of freshly distilled acetaldehyde and stirred slowly at room temperature for 30 mins. 14.622 Kg (91.504 mol) of bromine was added dropwise, after the dropwise addition, the reaction was carried out at 0-3°C for 3.5h, and the fraction was distilled under reduced pressure. The fractions (3.6 kPa) and 11.002 Kg (65.883 mol) of 80-82 ° C were collected and identified as bromoacetaldehyde ethylene glycol, the yield is 79.2%, the content is more than 95%.
References:
Beijing Yifang Biological Technology Co., Ltd.;Wang, Jiao;Shi, Qingdong CN105418612, 2016, A Location in patent:Paragraph 0028; 0039; 0040
7252-83-7
418 suppliers
$5.00/10g
107-21-1
1370 suppliers
$10.00/25g
4360-63-8
313 suppliers
$5.00/5g
107-21-1
1370 suppliers
$10.00/25g
2032-35-1
490 suppliers
$5.00/10g
4360-63-8
313 suppliers
$5.00/5g
497-26-7
105 suppliers
$25.00/5 g
4360-63-8
313 suppliers
$5.00/5g
