ChemicalBook CAS DataBase List 2-Phenylimidazole

2-Phenylimidazole synthesis

10synthesis methods

Product Name:2-Phenylimidazole
CAS Number:670-96-2
Molecular formula:C9H8N2
Molecular Weight:144.17

100-52-7 Synthesis

100-52-7
952 suppliers
$17.30/2g

107-15-3
9 suppliers
$11.19/25ML

670-96-2
425 suppliers
$6.00/10g

Yield:670-96-2 90%

Reaction Conditions:

with tribromide-modified silica-coated magnetic nanoparticles (Fe₃O₄/SiO₂/(CH₂)3N+Me₃Br₃) in neat (no solvent) at 80; for 0.25 h;Green chemistry;

Steps:

2.3. General procedure for the synthesis of imidazole, benzimidazole, benzothiazole, and perimidine derivatives
General procedure: A stirred solution of the substrate (1 mmol), aryl adehyde (1 mmol),and tribromide-modified silica-coated magnetic nanoparticles (Fe3O4/SiO2/(CH2)3N+Me3Br3-, 0.007 g) was heated 80 °C. After completion of the reaction [TLC (AcOEt/hexane 1:3) monitoring], EtOH (10 mL) was added. The catalyst was recovered by an external magnet, and thereaction mixture was poured into ice-water (30 mL). The solid productwas filtered, washed with ice-water, and dried.

References:

Farrokhi, Azita;Ghodrati, Keivan;Yavari, Issa [Catalysis Communications,2015,vol. 63,p. 41 - 46]