[2-(piperidin-1-ylmethyl)phenyl]methanol synthesis
- Product Name:[2-(piperidin-1-ylmethyl)phenyl]methanol
- CAS Number:91271-61-3
- Molecular formula:C13H19NO
- Molecular Weight:205.3
110-89-4
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$15.96/100ML
643-79-8
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$9.00/1g
91271-61-3
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$102.00/1g
Yield:91271-61-3 41%
Reaction Conditions:
Stage #1: piperidine;o-phthalic dicarboxaldehydewith titanium(IV) isopropylate in ethanol at 20; for 1 h;
Stage #2: with sodium tetrahydroborate in ethanol; for 8 h;
References:
Miko, Tibor;Ligneau, Xavier;Pertz, Heinz H.;Arrang, Jean-Michel;Ganellin, C. Robin;Schwartz, Jean-Charles;Schunack, Walter;Stark, Holger [Bioorganic and Medicinal Chemistry,2004,vol. 12,# 10,p. 2727 - 2736]