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(2S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid synthesis

1synthesis methods
24424-99-5 Synthesis
Di-tert-butyl dicarbonate

24424-99-5
819 suppliers
$13.50/25G

(2S)-5-Methylpyrrolidine-2-carboxylic acid

681128-94-9
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(2S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid

374929-20-1
18 suppliers
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Yield:-

Reaction Conditions:

with sodium hydroxide in 1,4-dioxane;

References:

Barrow, James C;Nantermet, Philippe G;Selnick, Harold G;Glass, Kristen L;Ngo, Phung L;Young, Mary Beth;Pellicore, Janetta M;Breslin, Michael J;Hutchinson, John H;Freidinger, Roger M;Condra, Cindra;Karczewski, Jerzy;Bednar, Rodney A;Gaul, Stanley L;Stern, Andrew;Gould, Robert;Connolly, Thomas M [Bioorganic and Medicinal Chemistry Letters,2001,vol. 11,# 20,p. 2691 - 2696]

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