ChemicalBook CAS DataBase List 3-FLUORO-2-METHOXYBENZALDEHYDE

3-FLUORO-2-METHOXYBENZALDEHYDE synthesis

11synthesis methods

Product Name:3-FLUORO-2-METHOXYBENZALDEHYDE
CAS Number:74266-68-5
Molecular formula:C8H7FO2
Molecular Weight:154.14

394-50-3 Synthesis

394-50-3
243 suppliers
$9.00/250mg

74-88-4
351 suppliers
$15.00/10g

74266-68-5
156 suppliers
$25.60/1g

Yield: 88%

Reaction Conditions:

with caesium carbonate in N,N-dimethyl-formamide at 20; for 2 h;Inert atmosphere;

Steps:

18
Preparation 18; 3-Fluoro-2-methoxy-benzaldehyde; A mixture of 3-fluorosalicylaldehyde (3.52 g, 25.12 mmol) and cesium carbonate (20.46 g, 62.81 mmol) in N,N-dimethylformamide (30 mL) is treated with iodomethane (3.13 mL, 50.2 mmol) and stirred at room temperature under nitrogen for 2 h. The reaction mixture is diluted with diethyl ether (150 mL) and washed with 0.5 M hydrochloric acid (2 x 150 mL). The organic portion is dried over anhydrous sodium sulfate, filtered, and concentrated to afford 3.42 g (88%) of the title compound as a clear oil. ¹H NMR (400 MHz, CDCl₃) δ 7.59 (d, IH), 7.32 (dd, IH), 7.04 (m, IH), 4.04 (s, 3H).

References:

Location in patent:Page/Page column 38-39

394-50-3 Synthesis

394-50-3
243 suppliers
$9.00/250mg

77-78-1
322 suppliers
$19.69/1ml

74266-68-5
156 suppliers
$25.60/1g

References

367-12-4 Synthesis

367-12-4
435 suppliers
$5.00/10g

74266-68-5
156 suppliers
$25.60/1g

References

2105-94-4 Synthesis

2105-94-4
363 suppliers
$6.00/5g

74266-68-5
156 suppliers
$25.60/1g

References

1526-17-6
191 suppliers
$6.00/1g

74266-68-5
156 suppliers
$25.60/1g

References

3-FLUORO-2-METHOXYBENZALDEHYDE Related Search:

2-Fluoro-4-methoxybenzaldehyde 6-CHLORO-2-FLUORO-3-METHOXYBENZALDEHYDE 4-FLUORO-3-METHOXYBENZALDEHYDE 2-CHLORO-6-FLUORO-3-METHOXYBENZALDEHYDE 3-bromo-6-fluoro-2-methoxybenzaldehyde

HomePage | About Us | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Product Catalog | Links | Privacy | Terms | Product Manufacturers | New Products
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.