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ChemicalBook CAS DataBase List 3-TERT-BUTYLDIMETHYLSILYL-2-PROPYN-1-OL

3-TERT-BUTYLDIMETHYLSILYL-2-PROPYN-1-OL synthesis

7synthesis methods
18162-48-6 Synthesis
tert-Butyldimethylsilyl chloride

18162-48-6
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3-TERT-BUTYLDIMETHYLSILYL-2-PROPYN-1-OL

120789-51-7
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: 1.) n-BuLi / 1.) THF, hexane, -20 deg C, 1 h, 2.) THF, hexane, RT, overnight
2: conc. HCl / methanol / 2 h / Ambient temperature

References:

Bishop;Cottrell;Hands [Synthesis,1997,# 11,p. 1315 - 1320]