4-Chlorobenzophenone synthesis
- Product Name:4-Chlorobenzophenone
- CAS Number:134-85-0
- Molecular formula:C13H9ClO
- Molecular Weight:216.66
Yield:134-85-0 100%
Reaction Conditions:
with potassium phosphate;3,3-dimethyl-butan-2-one;C14H10Cl2N2O2Ru;tri tert-butylphosphoniumtetrafluoroborate in water;toluene at 100; for 24 h;
Steps:
4.5 General procedure for the C-C cross-coupling
General procedure: In a typical run, an oven-dried 10 mL round bottom flask was charged with a known mole percent of ruthenium catalyst, K3PO4 (1.0 mmol), p-substituted phenylboronic acid (1.25 mmol), ligand (0.05 mmol), arylaldehyde (0.5 mmol) and 2.0 mL toluene and 0.2 mL water as solvent. The flask was placed in a preheated oil bath at required temperature. After the specified time the flask was removed from the oil bath and water (20 mL) added, followed by extraction with ether (4 × 10 mL). The combined organic layers were washed with water (3 × 10 mL), dried over anhydrous Na2SO4, and filtered. Solvent was removed under vacuum. The residue was dissolved in hexane and analyzed by GCMS.
References:
Dey, Bikash Kali;Dutta, Jayita;Drew, Michael G.B.;Bhattacharya, Samaresh [Journal of Organometallic Chemistry,2014,vol. 750,p. 176 - 184]
119-56-2
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$13.00/5g
134-85-0
599 suppliers
$5.00/25g
18218-20-7
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$45.00/50mg
134-85-0
599 suppliers
$5.00/25g
