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4-ethylbutyrophenone synthesis

4synthesis methods
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Yield:35028-11-6 92%

Reaction Conditions:

Stage #1: butyryl chloridewith aluminum (III) chloride in 1,2-dichloro-ethane at 0; for 0.166667 h;Friedel-Crafts Acylation;
Stage #2: ethylbenzene in 1,2-dichloro-ethane at 50; for 1 h;Friedel-Crafts Acylation;

References:

Siddaraju, Yogesh;Prabhu, Kandikere Ramaiah [Organic and Biomolecular Chemistry,2015,vol. 13,# 24,p. 6749 - 6753] Location in patent:supporting information