4-FLUOROPHENACYL THIOCYANATE synthesis
- Product Name:4-FLUOROPHENACYL THIOCYANATE
- CAS Number:43045-16-5
- Molecular formula:C9H6FNOS
- Molecular Weight:195.21
333-20-0
420 suppliers
$13.50/100G
403-29-2
315 suppliers
$8.00/5g
43045-16-5
24 suppliers
$64.00/1g
Yield:43045-16-5 95%
Reaction Conditions:
in acetonitrile; for 2 h;Reflux;
Steps:
52.1 Step 1:
1-(4-fluorophenyl)-2-thiocyanatoethanone
Potassium thiocyanate (2.7 g, 27.7 mmol) was added to a solution of 2-bromo-1-(4-fluorophenyl)ethanone (3 g, 13.8 mmol) in acetonitrile (30 mL), and the mixture was heated to reflux for 2 h.
The reaction solution was concentrated to give 1-(4-fluorophenyl)-2-thiocyanatoethanone 0149A in the form of a white solid (2.5 g, 95%). LCMS (ESI) [M+H]+=196.11.80 min (Method B).
References:
US2020/369676,2020,A1 Location in patent:Paragraph 1159-1160
7677-24-9
367 suppliers
$19.00/5g
403-42-9
533 suppliers
$5.00/10g
43045-16-5
24 suppliers
$64.00/1g
540-72-7
408 suppliers
$13.50/100G
403-29-2
315 suppliers
$8.00/5g
43045-16-5
24 suppliers
$64.00/1g
403-42-9
533 suppliers
$5.00/10g
43045-16-5
24 suppliers
$64.00/1g