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ChemicalBook CAS DataBase List (4-Fluorophenyl)acetone
459-03-0

(4-Fluorophenyl)acetone synthesis

9synthesis methods
4-Fluorophenyl acetone synthesis methods are mainly the following: (1) 4-fluorophenyl derivatives and acetone in the presence of catalysts such as manganese acetate to obtain; (2) α-cyanoacetone-based m-fluorobenzene and sulfuric acid reaction can also be
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Yield:459-03-0 94%

Reaction Conditions:

with lithium bromide in tetrahydrofuran;diethyl ether; for 1 h;Heating;

References:

Werbel;Cook;Elslager;Hung;Johnson;Kesten;McNamara;Ortwine;Worth [Journal of Medicinal Chemistry,1986,vol. 29,# 6,p. 924 - 939]

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