4-METHOXY-1-INDANONE synthesis
- Product Name:4-METHOXY-1-INDANONE
- CAS Number:13336-31-7
- Molecular formula:C10H10O2
- Molecular Weight:162.19
40731-98-4
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74-88-4
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13336-31-7
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$5.00/100mg
Yield:13336-31-7 99%
Reaction Conditions:
with potassium carbonate in acetone at 60; for 5 h;
Steps:
1.1a (1a): Preparation of 4-methoxy-1-indanone
4-Hydroxy-1-indanone (2.00 g, 13.5 mmol), potassium carbonate (7.5 g, 54.0 mmol)Add to acetone (40 mL), add methyl iodide (3.8 g, 27.0 mmol), warm to 60 ° C and stir for 5 h.TLC showed the reaction was complete, cooled to room temperature and poured into water.It was extracted twice with ethyl acetate, and the organic phase was washed with brine.Dried over anhydrous sodium sulfate and concentrated to dryness.4-methoxy-1-indanone (2.18 g, yield 99%) was obtained.
References:
Tsingtao Ocean Bio-pharmaceutical Institute;Chen Dong;Xu Tao;Zhao Weifeng;Qin Yuting;Zhang Shouhui;Shan Tiantian CN109776607, 2019, A Location in patent:Paragraph 0030; 0034-0037
67-56-1
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40731-98-4
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13336-31-7
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$5.00/100mg
6342-77-4
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13336-31-7
158 suppliers
$5.00/100mg
40731-98-4
236 suppliers
$6.00/1g
13336-31-7
158 suppliers
$5.00/100mg
40731-98-4
236 suppliers
$6.00/1g
77-78-1
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$19.69/1ml
13336-31-7
158 suppliers
$5.00/100mg