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ChemicalBook CAS DataBase List 4-[N,N-Bis(2-hydroxyethyl)amino]benzaldehyde

4-[N,N-Bis(2-hydroxyethyl)amino]benzaldehyde synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 99 percent / Et3N / tetrahydrofuran / 15 h / 35 °C
2: 1.) POCl3, 2.) AcONa / 1.) 70 deg C, 6 h, 2.) H2O, room temp., 1 h
3: 99 percent / Na2CO3 / methanol; H2O / 15 h / Ambient temperature

References:

Le Bouder, Thomas;Massiot, Philippe;Le Bozec, Hubert [Tetrahedron Letters,1998,vol. 39,# 38,p. 6869 - 6872]

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