Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 9,10-Bis(chloromethyl)anthracene
10387-13-0

9,10-Bis(chloromethyl)anthracene synthesis

3synthesis methods
Formaldehyde

50-00-0

Anthracene

120-12-7

9,10-Bis(chloromethyl)anthracene

10387-13-0

A dioxane (20 mL) solution of anthracene (1.78 g, 10 mmol), anhydrous ZnCl2 (1.64 g, 12 mmol), and paraformaldehyde (1.50 g, 50 mmol) was added sequentially to a reactor vessel equipped with a stirrer. A concentrated aqueous hydrochloric acid solution (40 mL) was added slowly and dropwise with stirring, and the reaction temperature was controlled to be below 50 °C. The reaction mixture was stirred at room temperature until homogeneous and then heated to a mild reflux condition and kept for 3 hours. After completion of the reaction, the mixture was allowed to stand at room temperature for 16 hours to complete crystallization. The resulting fine grained solid was separated by diafiltration and washed sequentially with deionized water and dioxane. The crude product was purified by recrystallization with toluene to give 1.8 g of light yellow solid product in 64.1% yield. The structure of the product was confirmed by 1H NMR (500 MHz, CDCl3): δ 8.40 (m, 4H), 7.62 (m, 4H), 5.61 ppm (s, 4H).

-

Yield:10387-13-0 92%

Reaction Conditions:

with hydrogenchloride in acetic acid at 60; for 20 h;

References:

Cloninger, Mary J.;Whitlock [Journal of Organic Chemistry,1998,vol. 63,# 18,p. 6153 - 6159]

FullText

9,10-Bis(chloromethyl)anthracene Related Search: