Biscresolfluorene synthesis
- Product Name:Biscresolfluorene
- CAS Number:88938-12-9
- Molecular formula:C27H22O2
- Molecular Weight:378.46
Yield:88938-12-9 92%
Reaction Conditions:
with 3-mercaptopropionic acid in chlorobenzene at 140; for 6 h;Temperature;Solvent;Reagent/catalyst;
Steps:
1; 2; 9; 11.2 Example 9:
288g of 9-fluorenone, 600g of o-methylphenol, 200g of activated clay catalyst, 16g of 3-mercaptopropionic acid, 2500g of chlorobenzene were sequentially added to a 5KL three port equipped with a stirrer, thermometer and water separator (with condenser) In the flask, the mixture was stirred, heated to reflux (140 ° C) and separated by water, and reacted for 6 hours. After the reaction, the mixture was filtered while hot, and the residue was recovered at 120 ° C for the next reaction. The filtrate was cooled to 10 ° C and then incubated for 1 hour. A crude gray product was obtained, which was recovered and used in the next reaction of the product; the crude product was recrystallized from toluene-methanol to give a white solid, 9,9-bis(3-methyl-4-hydroxyphenyl)indole product, 556.4 g. The yield was 92%, and the melting point was 218.6 to 220.2 ° C, and the HPLC purity was 99.5%.
References:
CN108863728,2018,A Location in patent:Paragraph 0030-0033; 0046; 0047; 0050; 0053; 0054
486-25-9
454 suppliers
$5.00/25g
95-48-7
429 suppliers
$18.00/25g
107-96-0
513 suppliers
$6.00/25g
88938-12-9
116 suppliers
$6.00/5g