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ChemicalBook CAS DataBase List BOC-N-ME-DL-PHG-OH

BOC-N-ME-DL-PHG-OH synthesis

2synthesis methods
24424-99-5 Synthesis
Di-tert-butyl dicarbonate

24424-99-5
816 suppliers
$13.50/25G

74641-60-4 Synthesis
N-ME-DL-PHENYLGLYCINE

74641-60-4
44 suppliers
$60.00/100mg

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Yield:30925-08-7 88%

Reaction Conditions:

with tetramethyl ammoniumhydroxide

Steps:

14.B14 Example 14; B14; [tert-butoxycarbonyl)methylamino](phenyl)acetic acid

[tert-butoxycarbonyl)methylamino](phenyl)acetic acid (1.42 g, 88%) was isolated as a white solid from N-methylphenylglycine (1.0 g, 6.05 mmol), tetramethylammonium hydroxide (1.10 g, 6.05 mmol) and (BOC)2O (2.78 mL, 12.1 mmol).

References:

WO2004/22534,2004,A1 Location in patent:Page 62

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