Bromo-PEG4-t-butyl ester synthesis
- Product Name:Bromo-PEG4-t-butyl ester
- CAS Number:564476-32-0
- Molecular formula:C15H29BrO6
- Molecular Weight:385.29
581065-94-3
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564476-32-0
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$90.00/50mg
Yield: 90%
Reaction Conditions:
with lithium bromide in N,N-dimethyl-formamide at 80; for 1 h;
Steps:
88.8 (8) Synthesis of Compound 118:
Compound 117 (10 g, 21.0 mmol) and lithium bromide (4.8 g, 31.5 mmol) were dissolved in 30 mL of N,N-dimethylformamide and heated to 80 °C for 1 h. Rotary evaporation under reduced pressure and N,N- dimethylformamide, water and extracted three times with dichloromethane, the organic phases were combined and dried over anhydrous sodium sulfate, and rotary evaporation under reduced pressure, Column chromatography (CH2C12), to give a pale yellow liquid, i.e., compound 118 (7.3g, 90%).
References:
Zhongshan Guang He Medical Treatment Technology Co., Ltd.;Zhu Linyong;Hua Yujie;Lin Qiuning;Zhang Yiqing;Bao Chunyan;Zhong Xuepeng CN109776451, 2019, A Location in patent:Paragraph 0668; 0669; 0678
558-13-4
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518044-32-1
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564476-32-0
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$90.00/50mg
518044-32-1
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$17.00/100mg
564476-32-0
75 suppliers
$90.00/50mg
![Bis[2-(2-hydroxyethoxy)ethyl] ether](/CAS/GIF/112-60-7.gif)
112-60-7
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564476-32-0
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1663-39-4
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564476-32-0
75 suppliers
$90.00/50mg