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ChemicalBook CAS DataBase List Clinafloxacin
105956-97-6

Clinafloxacin synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: Et3N / acetonitrile / 1.) reflux, 3 h, 2.) room temperature, 18 h
2: HCl, AcOH / 1.) 60 deg C, 4 h, 2.) room temperature, overnight

References:

Sanchez, Joseph P.;Domagala, John M.;Hagen, Susan E.;Heifetz, Carl L.;Hutt, Marland P.;et al. [Journal of Medicinal Chemistry,1988,vol. 31,p. 983 - 991]

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