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ChemicalBook CAS DataBase List Closantel

Closantel synthesis

4synthesis methods
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: sodium methylate; methanol / 3 h / 50 °C / Sealed tube
2: hydrazine hydrate; sodium hydroxide / diethylene glycol / 6 h / 200 °C / Sealed tube
3: toluene / 6 h / 50 °C / Reflux; Sealed tube

References:

Zhejiang University Of Technology Shangyu Institute Co., Ltd.;Fang Biao;Xu Meng;Ke Junliang CN109851526, 2019, A

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