ChemicalBook CAS DataBase List Enrofloxacin

Enrofloxacin synthesis

12synthesis methods

Product Name:Enrofloxacin
CAS Number:93106-60-6
Molecular formula:C19H22FN3O3
Molecular Weight:359.39

5308-25-8 Synthesis

5308-25-8
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$15.00/5G

86393-33-1 Synthesis

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

86393-33-1
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$15.00/25g

93106-60-6
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$6.00/1g

Yield:93106-60-6 97%

Reaction Conditions:

with nano iron oxide on ZrO₂ coated sulfonic acid in water; for 0.316667 h;Reflux;Solvent;Temperature;Reagent/catalyst;

Steps:

3.2. General Experimental Procedure

A mixture of 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 1a (1 mmol) and Nethylpiperazine2y (1.5 mmol) and n-FZSA (0.06 g) as catalystin H2O (5 ml) were heated under reflux for the appropriatetime. The reaction was monitored by TLC. After appropriatetime, the catalyst was separated using an externalmagnet and washed with hot ethanol (5 mL). The reactionmixture was then cooled to room temperature. The precipitatedsolid was collected by filtration, and recrystallized fromethanol 96% to give desired compound in high yields.

References:

Nakhaei, Ahmad;Ramezani, Shirin;Shams-Najafi, Sayyed Jalal;Farsinejad, Sadaf [Letters in Organic Chemistry,2018,vol. 15,# 9,p. 739 - 746]

5308-25-8 Synthesis

5308-25-8
442 suppliers
$15.00/5G