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ChemicalBook CAS DataBase List ethyl 2-phenylbutyrate

ethyl 2-phenylbutyrate synthesis

13synthesis methods
-

Yield: 25%

Reaction Conditions:

with tetrabutyl ammonium fluoride;tris[(1S,2S,5S)-myrtanyl dimethyl]silane in toluene at -30;Product distribution / selectivity;

Steps:


Enantioselectivities observed for reactions involving tris [(1S, 2S, [5S)-] mertynyldimethyl] silane [(F)] at various temperatures in toluene. MgBr2. [(ET20)] [2] was used in about 2 molar equivalents and all other Lewis acids were used in about 1 molar equivalents, relative to the substrate.

References:

CHIROGEN PTY LIMITED WO2004/18487, 2004, A1 Location in patent:Page 28

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