Ethyl 3-Cyclopropylpyrazole-4-carboxylate synthesis
- Product Name:Ethyl 3-Cyclopropylpyrazole-4-carboxylate
- CAS Number:1246471-38-4
- Molecular formula:C9H12N2O2
- Molecular Weight:180.2
64-17-5
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870704-26-0
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1246471-38-4
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$45.00/100mg
Yield: 119 mg
Reaction Conditions:
with sulfuric acidReflux;
Steps:
63
According to Scheme 8, (3-Cyclopropylpyrazole-4-carboxylic acid, 100 mg),After dissolving 50 μL of H2SO4 in 1 mL of ethanol (EtOH),Refluxed.After adjusting the pH to 6-7 with 1N NaOH, extracted with EA, dried with MgSO4,Concentrated under reduced pressure to obtain ethyl 3-cyclopropyl-1H-pyrazole-4-carboxylate (119 mg).
References:
Boryeong Pharmaceutical Co., Ltd.;Kim Seong-heon;Jeong Hui-jin;Nam Eun-hye;Park Jin-yeong;Lee Seok-ho;Yang Deok-mo;Lee Hui-jin KR2020/115934, 2020, A Location in patent:Paragraph 0545; 0549-0551
122-51-0
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24922-02-9
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1246471-38-4
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$45.00/100mg