ChemicalBook CAS DataBase List Isopropyl Itraconazole

Isopropyl Itraconazole synthesis

8synthesis methods

Product Name:Isopropyl Itraconazole
CAS Number:89848-49-7
Molecular formula:C34H36Cl2N8O4
Molecular Weight:691.61

38212-30-5
211 suppliers
$15.00/5G

89848-49-7
58 suppliers
inquiry

Yield:-

Steps:

Multi-step reaction with 8 steps
1: 67 percent / K₂CO₃ / dimethylsulfoxide / 120 °C
2: 74 percent / H₂, thiophene / 5percent Pd/C / 2-methoxy-ethanol; methanol / 50 °C / Heating
3: 61 percent / pyridine / CHCl₃ / 3 h
4: 63 percent / hydrazine hydrate / dioxane / 3 h / Heating
5: 28 percent / NaOAc / butan-1-ol
6: 47 percent / KOH / dimethylsulfoxide / 14 h
7: 86 percent / 48percent aq. HBr / Heating
8: 1.) NaH / 1.) Me₂SO, 50 deg C, 1 h, 2.) Me₂SO, 100 deg C, 3 h

References:

Heeres;Backx;Van Cutsem [Journal of Medicinal Chemistry,1984,vol. 27,# 7,p. 894 - 900]

1-(4-Methoxyphenyl)-4-(4-nitrophenyl)piperazine

74852-61-2
138 suppliers
inquiry

89848-49-7
58 suppliers
inquiry

References

1-(4-AMINOPHENYL)-4-(4-METHOXYPHENYL)PIPERAZINE

74852-62-3
165 suppliers
$26.57/5G

89848-49-7
58 suppliers
inquiry

References

74853-07-9 Synthesis

2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one

74853-07-9
60 suppliers
$55.00/10mg

89848-49-7
58 suppliers
inquiry

References

74852-89-4 Synthesis

Hydrazine Carboxamide,N-{4-[4(4-methoxyphenyl)-1-pipezinyl]phenyl}

74852-89-4
15 suppliers
inquiry

89848-49-7
58 suppliers
inquiry

References

Isopropyl Itraconazole Related Search:

DPUDRFOQNBKHMF-YZNIXAGQSA-N 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol Itraconazole 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- Itraconazole Impurity 24 Cis -Tosylate

HomePage | About Us | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Product Catalog | Links | Privacy | Terms | Product Manufacturers | New Products
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.