Loteprednol etabonate synthesis
- Product Name:Loteprednol etabonate
- CAS Number:82034-46-6
- Molecular formula:C24H31ClO7
- Molecular Weight:466.95
50-24-8
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$14.10/100mg
82034-46-6
347 suppliers
$28.00/5mg
Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: sodium periodate / methanol; water / 0.5 h / Heating; Large scale
2.1: triethylamine / dichloromethane / 0.5 h / 0 - 10 °C / Large scale
3.1: sodium ethanolate / N,N,N,N,N,N-hexamethylphosphoric triamide / 24 h / 20 °C / Large scale
3.2: 2 h / 20 °C / Large scale
References:
Shanghai Qingsong Pharmaceutical Co., Ltd.;Zhang, Jian;Chen, Xiaona;Gao, Junfeng;Zhang, Shubin;Tan, Zhouhong CN106554383, 2017, A
37927-29-0
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inquiry
82034-46-6
347 suppliers
$28.00/5mg