ChemicalBook CAS DataBase List Dimethyl phthalate

Dimethyl phthalate synthesis

14synthesis methods

Product Name:Dimethyl phthalate
CAS Number:131-11-3
Molecular formula:C10H10O4
Molecular Weight:194.18

Dimethyl phthalate is produced industrially from phthalic anhydride and methanol.

67-56-1 Synthesis

67-56-1
727 suppliers
$9.00/25ml

88-99-3 Synthesis

88-99-3
432 suppliers
$15.00/50g

131-11-3
577 suppliers
$14.00/25g

Yield:131-11-3 96%

Reaction Conditions:

with sulfuric acid for 24 h;Reflux;

Steps:

Synthesis of phthalic acid ester 3

Phthalic acid (2, 6.00 g, 36.2 mol) was dissolved in methanol (130 mL). After thatconc. sulfuric acid (6.80 mL) was slowly added dropwise. The reaction mixture wasstirred under reflux for 24 h. After cooling down to room temperature the solution wasconcentrated and added to a mixture of 200 mL dichloromethane/water (1:1). Theaqueous phase was extracted three times with dichloromethane. The combinedorganic layers were dried over magnesium sulfate and the solvent was removedunder reduced pressure. A yellow oil was obtained

References:

Peters, Morten K.;Herges, Rainer [Beilstein Journal of Organic Chemistry,2017,vol. 13,p. 2659 - 2662] Location in patent:supporting information

88-99-3 Synthesis

88-99-3
432 suppliers
$15.00/50g

616-38-6 Synthesis