5-HYDROXYTRYPTOPHOL
- CAS No.
- 154-02-9
- Chemical Name:
- 5-HYDROXYTRYPTOPHOL
- Synonyms
- NSC 84416;hydroxytryptophol;3-(2-Hydroxyethyl);5-HYDROXYTRYPTOPHOL;2H8]-5-Hydroxytryptophol;5-hydroxy-indole-3-ethano;5-HYDROXYINDOLE-3-ETHANOL;5-HYDROXYTRYPTOPHOL(5OHIEt);5-hydroxy-1h-indole-3-ethano;5-hydroxy-1h-indole-3-ethanol
- CBNumber:
- CB3250862
- Molecular Formula:
- C10H11NO2
- Molecular Weight:
- 177.2
- MDL Number:
- MFCD00047197
- MOL File:
- 154-02-9.mol
| Melting point | 111-113° |
|---|---|
| Boiling point | 435.2±30.0 °C(Predicted) |
| Density | 1.356±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 10.07±0.40(Predicted) |
| form | Solid |
| color | White to Light Red |
| FDA UNII | 52MNE52QA1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| RTECS | NL8512500 | |||||||||
| HS Code | 2933998090 | |||||||||
| NFPA 704 |
|
5-HYDROXYTRYPTOPHOL price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16114 | 5-hydroxy Tryptophol ≥98% | 154-02-9 | 5mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 16114 | 5-hydroxy Tryptophol ≥98% | 154-02-9 | 10mg | $55 | 2024-03-01 | Buy |
| Cayman Chemical | 16114 | 5-hydroxy Tryptophol ≥98% | 154-02-9 | 25mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 16114 | 5-hydroxy Tryptophol ≥98% | 154-02-9 | 100mg | $275 | 2024-03-01 | Buy |
| TRC | H976000 | 5-HydroxyTryptophol | 154-02-9 | 10mg | $65 | 2021-12-16 | Buy |
5-HYDROXYTRYPTOPHOL Chemical Properties,Uses,Production
Chemical Properties
Off-White Crystalline Powder
Uses
A metabolite of Tryptophan (T947200).
Definition
ChEBI: 5-Hydroxytryptophol is a member of indoles.
Hazard
A reproductive hazard.
Biological Activity
5-hydroxy tryptophol is a metabolite of tryptophan.tryptophan (encoded by the codon ugg) is an α-amino acid that is used in the biosynthesis of proteins. tryptophan has an α-amino group, an α-carboxylic acid group, and a side chain indole, demonstrating it as a non-polar, aromatic amino acid. tryptophan is critical in humans, but the body cannot synthesize it and therefore tryptophan must be obtained from the diet. tryptophan is also found to be a precursor to the neurotransmitters serotonin and melatonin.
in vitro
in previous studies, 5-hydroxy tryptophol was identified as a metabolite of tryptophan that was formed by the alcohol dehydrogenase-catalyzed reduction of the serotonin intermediate, 5-hydroxyindoleacetaldehyde. moreover, depending on the tissue nad/nadh ratio, the acetaldehyde intermediate could also be oxidized by aldehyde dehydrogenase to form 5-hydroxyindoleacetic acid. therefore, the ratio of 5-hydroxy tryptophol to 5-hydroxyindoleacetic acid could be used as a biomarker for recent alcohol consumption [1,2].
References
[1] yokoyama, m. t. and carlson, j.r. dissimilation of tryptophan and related indolic compounds by ruminal microorganisms in vitro. appl.microbiol. 27(3), 540-548 (1974).
[2] beck, o. ,stephanson, n.,btthcer, m., et al. biomarkers to disclose recent intake of alcohol: potential of 5-hydroxytryptophol glucuronide testing using new direct uplc-tandem ms and elisa methods. alcohol & alcoholism 42(4), 321-325 (2007).
5-HYDROXYTRYPTOPHOL Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
5-HYDROXYTRYPTOPHOL Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9651 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| R&D Scientific Inc. | +12266000236 | sales@rdscientific.com | Canada | 1263 | 58 |
View Lastest Price from 5-HYDROXYTRYPTOPHOL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-25 | 5-HYDROXYTRYPTOPHOL
154-02-9
|
US $0.01 / KG | 1KG | 95%-99% | 1kg; 100kg； 500kg | Career Henan Chemical Co |
-
- 5-HYDROXYTRYPTOPHOL
154-02-9
- US $0.01 / KG
- 95%-99%
- Career Henan Chemical Co