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X-PHOS

X-PHOS Structure
X-PHOS structure
CAS No.
564483-18-7
Chemical Name:
X-PHOS
Synonyms
5-BROMO-4-CHLORO-3-INDOLYL PHOSPHATE;2-Dicyclohexylphosphino-2;dicyclohexyl(2',4',6'-triisopropyl-[1,1'-biphenyl]-2-yl)phosphane;X-PH0S;dicyclohexyl-[2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane;X-PHOS;98% XPhos;XPhos 97%;2-(DicycL;XPhos, >=98%
CBNumber:
CB3357527
Molecular Formula:
C33H49P
Molecular Weight:
476.72
MDL Number:
MFCD04117682
MOL File:
564483-18-7.mol
MSDS File:
SDS
Last updated:2024-03-13 17:04:40
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X-PHOS Properties

Melting point 187-190 °C(lit.)
Boiling point 569.8±50.0 °C(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility Benzene (Slightly)
form Powder
color white
Sensitive Air Sensitive
Stability Air Sensitive
InChIKey UGOMMVLRQDMAQQ-UHFFFAOYSA-N
CAS DataBase Reference 564483-18-7(CAS DataBase Reference)
FDA UNII R271FU23T8

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H351
Precautionary statements  P280
Hazard Codes  Xn
Risk Statements  36/37/38-22-40
Safety Statements  37/39-26-36/37
WGK Germany  3
TSCA  No
HS Code  29319090
NFPA 704
0
2 0

X-PHOS price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 638064 XPhos 97% 564483-18-7 1g $92.5 2024-03-01 Buy
Sigma-Aldrich 638064 XPhos 97% 564483-18-7 5g $171 2024-03-01 Buy
TCI Chemical D5038 2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl >98.0%(GC) 564483-18-7 1g $98 2024-03-01 Buy
TCI Chemical D5038 2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl >98.0%(GC) 564483-18-7 5g $288 2024-03-01 Buy
Strem Chemicals 15-1149 2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl, min. 98% XPhos 564483-18-7 500mg $33 2024-03-01 Buy
Product number Packaging Price Buy
638064 1g $92.5 Buy
638064 5g $171 Buy
D5038 1g $98 Buy
D5038 5g $288 Buy
15-1149 500mg $33 Buy

X-PHOS Chemical Properties,Uses,Production

Reaction

  1.  Exceptional ligands for Pd-catalyzed amination and amidation of aryl sulfonates.
  2.  Ligand used for the Pd-catalyzed Suzuki-Miyaura coupling reaction and carbonyl enolate coupling.
  3.  Ligand used for the chemoselective amination of aryl chlorides.
  4.  Ligand used for the Pd-catalyzed borylation of aryl chlorides, for the formation of trifluoroborates.
  5.  Ligand used for the Pd-catalyzed amination of vinyl halides and triflates.
  6.  Ligand used for the Pd-catalyzed three-component synthesis of indoles.
  7.  Ligand used for the Pt-catalyzed regioselective hydrosilylation of functionalized terminal arylalkynes.
  8.  Ligand used for the Pd-catalyzed synthesis of carbazoles.
  9.  Ligand used for the Pd-catalyzed Suzuki-Miyaura coupling of aryl chloride and NHC-boranes.
  10.  Ligand used for the direct arylation of picoline N-oxide.
  11.  Ligand used for the Negishi coupling of 2-heterocyclic organozinc reagents.
  12.  Catalyst for a phosphine-catalyzed Heine reaction.
  13.  Ligand used for the palladium-catalyzed oxidative coupling of indoles and heteroarenes.
  14.  Ligand used for the silver-catalyzed hydrogenation of aldehydes.
  15.  Ligand used for the palladium-catalyzed cyanation of heterycyclic halides.
Reactions of 564483-18-7_1
Reactions of 564483-18-7_2
Reactions of 564483-18-7_3
Reactions of 564483-18-7_4

Chemical Properties

White crystalline powder

Uses

Exceptional ligands for Pd-catalyzed amination and amidation of aryl sulfonates. XPHOS is used as a regent in the synthesis of novel [1,2,4]triazolo[4,3-a]pyrazine derivatives as potential selective c-met inhibitors with improved pharmacokinetic properties.

Uses

suzuki reaction

General Description

This product has been enhanced for catalytic efficiency.

X-PHOS synthesis

21524-34-5
16523-54-9
583-53-9
564483-18-7
Synthesis of X-PHOS from 1-BROMO-2,4,6-TRIISOPROPYLBENZENE and Dicyclohexylchlorophosphine and 1,2-Dibromobenzene

X-PHOS Preparation Products And Raw materials

Raw materials

2-Bromochlorobenzene Dicyclohexylchlorophosphine Carbon tetrachloride Hydroquinone Tetrahydrofuran
1,3,5-Triisopropylbenzene Ethyl acetate Copper(I) chloride Government regulation Dichloromethane
Methanol Iron Magnesium Dicyclohexylphosphinbromid 1-BROMO-2,4,6-TRIISOPROPYLBENZENE

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Preparation Products

XPhos Pd G4 XPhos Pd G1

X-PHOS Suppliers

Global( 470)Suppliers
Supplier Tel Email Country ProdList Advantage
XINXIANG RUNYU MATERIAL CO., LTD. 		+86-13592593621; +8613592593621 sales@runvmat.com China 407 58
Puyang Huicheng Electronic Materials Co., Ltd.
+86-0393-+86-0393-8910800 +8615839383373 info@huichengchem.com China 516 58
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12456 58
Shanghai UCHEM Inc. 		+862156762820 +86-13564624040 sales@myuchem.com China 6710 58
Shanghai Affida new material science and technology center 		+undefined15081010295 2691956269@qq.com China 359 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1807 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
Supplier Advantage
XINXIANG RUNYU MATERIAL CO., LTD. 		58
Puyang Huicheng Electronic Materials Co., Ltd.
58
Hebei Mojin Biotechnology Co., Ltd 		58
Shanghai UCHEM Inc. 		58
Shanghai Affida new material science and technology center 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55

Related articles

View Lastest Price from X-PHOS manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl pictures 2024-04-26 2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl
564483-18-7
 US $32.00 / kg 1kg 99% 200mt Jinan Finer Chemical Co., Ltd
X-PHOS pictures 2024-03-13 X-PHOS
564483-18-7
 US $0.00-0.00 / kg 1kg 99 50000KG/month Shanghai Affida new material science and technology center
2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl pictures 2024-02-23 2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl
564483-18-7
 US $26.00-461.00 / g 25g 0.99 100kg Shanghai UCHEM Inc.
  • X-PHOS pictures
  • X-PHOS
    564483-18-7
  • US $0.00-0.00 / kg
  • 99
  • Shanghai Affida new material science and technology center

X-PHOS Spectrum

X-PHOS(564483-18-7)1HNMRX-PHOS(564483-18-7)31PNMRX-PHOS(564483-18-7)FT-IR

564483-18-7(X-PHOS)Related Search:

5-BROMO-4-CHLORO-3-INDOLYL PHOSPHATE DIPOTASSIUM SALT 2-(Dicyclohexylphosphino)biphenyl DI-N-PENTYLPHENYLPHOSPHINE DIBUTYLPHENYLPHOSPHINE 2-(Dicyclohexylphosphino)-2'-methylbiphenyl
X-PHOS Dicyclohexylphenylphosphine 5-BROMO-4-CHLORO-3-INDOLYL PHOSPHATE DISODIUM SALT PNP-PHOS K PNP-PHOS 2 CHX
PNP-PHOS DINA HEXAHYDRATE 5-Bromo-4-chloro-3-indolyl phosphate hydrate disodium salt PHOS-ALPHA-D-GLC 2H2O 5-Bromo-4-chloro-3-indolyl phosphate p-toluidine salt PNP-PHOS DINA
CYCLOHEXYLPHOSPHINE DICYCLOHEXYLPHOSPHINE GOAT F(AB')2 ANTI-HUMAN LAMBDA (F+B) ALK PHOS

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X-PHOS 2-(DICYCLOHEXYLPHOSPHINO)-2',4',6'-TRI-I-PROPYL-1,1'-BIPHENYL 2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISO-PROPYL-1,1'-BIPHENYL 2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISOPROPYLBIPHENYL 2-Dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl, X-PHOS 2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl,min.98%X-Phos 2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl, 98+% ChemDose(R), X-Phos impregnated tablets, 2-Dicyclohexylphosphino-2μ,4μ,6μ-triisopropylbiphenyl impregnated tablets X-Phos, ChemDose(R) tablets 2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbip 2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1, 2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl ,97% 2-Dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl,XPhos 2-Dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl, 98+% X-PHOS 98% XPhos 2-(DicyclohexylphosphiNA)-2',4',6'-triisopropylbiphenyl Dicyclohexyl(2',4',6'-triisopropyl-[1,1'-biphenyl]-2-yl)phosphine 2,,4',6'-Diisopropyl-1,1'-biphenyl-2-yldicyclohexylphosphine 2-(Dicyclohexylphosphino)-2',4 2-(Dicyclohexylphosphanyl)-2',4',6'-tris(isopropyl)biphenyl Dicyclohexyl[2',4',6'-tris(prop-2-yl)biphenyl-2-yl]phosphine, Dicyclohexyl[2',4',6'-tris(prop-2-yl)biphenyl-2-yl]phosphane, X-phos Phosphine, dicyclohexyl[2',4',6'-tris(1-Methylethyl)[1,1'-biphenyl]-2-yl]- XPhos 97% 2-(DICYCLOHEXYLPHOSPHINO)-2',4',6'-TRI-I-PROPYL-1,1'-BIPHENYL OR X-PHOS (2-(2,4,6-triisopropylphenethyl)phenyl)dicyclohexylphosphine X-PHOS,2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl XPhos, >=98% Dicyclohexyl[2-(2,4,6-triisopropylphenyl)phenyl]phosphane X-Phos, ChemDose? tablets 2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl, min. 98% dicyclohexyl[2',4',6'-tris(propan-2-yl)-[1,1'-biphenyl]-2-yl]phosphane -biphenyl]-2-yl]phosphane (2-(2,4,6-triisopropylphenethyl)phenyl)dicyclohexylphosphine(X-Phos) 2-(DicycL phosphino)-2',4',6'-tri-i-propyL Dicyclohexyl(2',4',6'-triisopropylbiphenyl-2-yl)phosphine 2-Dicyclohexylphosphino-2',4',6'-t [2'-(methylamino)-[1,1'-biphenyl]-2-yl]palladio methanesulfonate X-Phos, ChemDose(TM) tablets -1,1'-biphenyL 2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl,min.98% X-Phos ( 2-dicyclohexylphosphino-2’,4’,6’-triisopropylbiphenyl) 2-Dicyclohexylphosphino-2',4',6'-trisopropyl-1,1'-biphenyl(X-phos) 2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISO-PROPYL-1,1'-BIPHENYL,xphos X-Phos (2-Dicyclohexylphosphino-2,4,6-Triisopropylbiphenyl) extrapure, 98% 5-BROMO-4-CHLORO-3-INDOLYL PHOSPHATE 2-Dicyclohexylphosphino-2 dicyclohexyl(2',4',6'-triisopropyl-[1,1'-biphenyl]-2-yl)phosphane X-PH0S dicyclohexyl-[2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane 2-Dicyclohexylphosphate-2 ', 4', 6 '- triisopropylbiphenyl 2-dicyclohexylphosphine 2',4',6' -triisopropyl biphenyl Abemaciclib Impurity 31 Abemaciclib Impurity 39 2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl 2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISO-PROPYL-1,1'-BIPHENYL XPhos(2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl) 2,,4',6'-Diisopropyl-1,1'-biphenyl-2-yldicyclohexylphosphine