Glycine ethyl ester hydrochloride
- CAS No.
- 623-33-6
- Chemical Name:
- Glycine ethyl ester hydrochloride
- Synonyms
- ETHYL GLYCINATE HYDROCHLORIDE;GLYCINE ETHYL ESTER;GLYCINE ETHYL ESTER HCL;GEE;H-GLY-OET HCL;ETHYL AMINOACETATE HYDROCHLORIDE;usafdo-10;Gly-OEt HCl;ycine EthyL;GLYCINE-OET HCL
- CBNumber:
- CB5275670
- Molecular Formula:
- C4H9NO2.ClH
- Molecular Weight:
- 139.58
- MDL Number:
- MFCD00012871
- MOL File:
- 623-33-6.mol
- MSDS File:
- SDS
Melting point | 145-146 °C(lit.) |
---|---|
Density | 1.371 g/cm3 |
storage temp. | 2-8°C |
solubility | >1000 g/L (20 °C) |
pka | pK1:7.66(+1) (25°C) |
form | Crystalline Powder |
color | White |
PH | 2.9 (10g/l, H2O, 20℃) |
Odor | Odorless |
Water Solubility | >1000 g/L (20 ºC) |
Sensitive | Hygroscopic |
BRN | 3594034 |
InChIKey | TXTWXQXDMWILOF-UHFFFAOYSA-N |
CAS DataBase Reference | 623-33-6(CAS DataBase Reference) |
EPA Substance Registry System | Glycine, ethyl ester, hydrochloride (623-33-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05 |
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Signal word | Danger | |||||||||
Hazard statements | H318 | |||||||||
Precautionary statements | P280-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 41-36/37/38 | |||||||||
Safety Statements | 26-39-24/25-37/39 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | MC0525000 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29224995 | |||||||||
NFPA 704 |
|
Glycine ethyl ester hydrochloride price More Price(39)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | G6503 | Glycine ethyl ester hydrochloride 99% | 623-33-6 | 5G | $35.4 | 2024-03-01 | Buy |
Sigma-Aldrich | G6503 | Glycine ethyl ester hydrochloride 99% | 623-33-6 | 100g | $65.6 | 2024-03-01 | Buy |
Sigma-Aldrich | G6503 | Glycine ethyl ester hydrochloride 99% | 623-33-6 | 500g | $97.7 | 2024-03-01 | Buy |
TCI Chemical | G0102 | Glycine Ethyl Ester Hydrochloride >99.0%(T) | 623-33-6 | 25g | $19 | 2024-03-01 | Buy |
TCI Chemical | G0102 | Glycine Ethyl Ester Hydrochloride >99.0%(T) | 623-33-6 | 500g | $75 | 2024-03-01 | Buy |
Glycine ethyl ester hydrochloride Chemical Properties,Uses,Production
Chemical Properties
Crystalline
Uses
Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N?-ethylcarbodiimide (EDC) for carboxyl-foot printing studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH. It is mainly used as a pharmaceutical raw material. Glycine ethyl ester hydrochloride is an important intermediate for preparing chrysanthemic acid or two chlorine chrysanthemic acid and is mainly used in the synthesis of anti-inflammatory drugs, but also can be used for the synthesis of four imidazole acetic acid.
Uses
As a Glycine (G615990) ester, Glycine ethyl ester hydrochloride can be used as parakeratosis inhibitor and external composition for skin.
Synthesis
A production method for glycine ethyl ester hydrochloride:First add dehydrated ethanol in 1# reactor, pass into anhydrous hydrogen chloride to obtain hydrochloric acid-ethanol solution; Add a certain amount of triethyl orthoformate and glycine and hydrochloric acid-ethanol solution in 2# reactor, in the Reaction under action; after the reaction is complete, distill and recover ethanol and ethyl formate; then add alcohol-ether mixture, wash, filter, concentrate, recrystallize, and vacuum dry to obtain ethyl glycine hydrochloride.
Purification Methods
Crystallise it from absolute EtOH or EtOH/Et2O. [Marvel Org Synth Coll Vol II 310 1943, Beilstein 4 II 780, 4 III 3 75.]
Glycine ethyl ester hydrochloride Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of5
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
DONBOO AMINO ACID COMPANY | +8613063595538 | donboo@donboo.com | China | 9365 | 58 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1807 | 55 |
Shandong Believe Chemical PTE.LTD | +86-18553607090 +8618553607090 | 1093908296@qq.com | China | 1672 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12446 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5886 | 58 |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 2990 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
Sichuan HongRi Pharma-Tech Co.,Ltd | +86-028-64841719 +8617390183901 | daisy@enlaibio.com | China | 1106 | 58 |
Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 | info@deshangchem.com | China | 645 | 58 |
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 885 | 50 |
View Lastest Price from Glycine ethyl ester hydrochloride manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-24 | H-Gly-Oet.HCl
623-33-6
|
US $0.00-0.00 / kg | 1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | ||
2024-09-23 | Glycine ethyl ester hydrochloride
623-33-6
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | ||
2024-09-18 | Glycine ethyl ester hydrochloride
623-33-6
|
US $0.00-0.00 / kg | 1kg | 98%min | 10000kg | WUHAN FORTUNA CHEMICAL CO., LTD |
- H-Gly-Oet.HCl
623-33-6
- US $0.00-0.00 / kg
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
- Glycine ethyl ester hydrochloride
623-33-6
- US $5.00-2.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
- Glycine ethyl ester hydrochloride
623-33-6
- US $0.00-0.00 / kg
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD