BCL2 inhibitor ABT-199

ABT-199(venetoclax, RG7601, GDC-0199) is a new selective small molecule inhibitor of BCL-2 that appears to spare platelets while achieving potent antitumor activity.

Mar 25,2025  API

Side effects of afatinib dimaleate

Afatinib dimaleate, the dimaleate form of afatinib, is an orally bioavailable anilinoquinazoline derivative that is an inhibitor of the epidermal growth factor receptor (ErbB; EGFR) family of receptor

Mar 25,2025  API

Dextrin Unveiled: From Basic Concepts to Gluten

Dextrins are a category that includes several different carbohydrate strains that are produced by the hydrolysis of starch.

Mar 25,2025  Supplements

2,2'-Dithiosalicylic acid: Synthesis and Identification

2,2'-Dithiosalicylic Acid is used as an intermediate for the synthesis of pharmaceuticals, dyes, photochemicals (thioxanthones) and biocides (proxel).

Mar 25,2025  Chemical Materials

Does Pralsetinib need to be reduced in patients with liver impairment?

Pralsetinib is a kinase inhibitor used to treat metastatic rearranged during transfection (RET) fusion-positive non-small cell lung cancer.

Mar 25,2025  Biochemical Engineering

Application Research of n-Heptadecane

n-Heptadecane is widely used in many fields due to its unique properties, such as cleaning agents, fuel additives, etc.

Mar 25,2025  Chemical Materials

Sulfadoxine: Uses, Safety, and Resistance

Sulfadoxine is predominantly used in combination with pyrimethamine, commonly known as Fansidar, for the treatment of Plasmodium falciparum.

Mar 25,2025  API

Relugolix: Development Background and Mechanism of Action

Relugolix is ??a GnRH antagonist, or gonadotropin-releasing hormone receptor antagonist, used to treat prostate cancer in men and uterine fibroids in women.

Mar 24,2025  Biochemical Engineering

What is the use of lenvatinib mesylate?

Lenvatinib mesylate, a first-line anticancer agent for the treatment of unresectable hepatocellular carcinoma, is a BCS class II drug with low aqueous solubility.

Mar 24,2025  API

Function and mechanism of action of Fisetin in cancer

Fisetin has been shown to inhibit invasion and migration of various types of cancer cells.

Mar 24,2025  API
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