The introduction of Cenobamate (SQ 109)
Cenobamate is the latest approved antiepileptic drug in focal epilepsy, and its mode of action is thought to be mediated by blocking voltage-gated sodium channels and interacting with the GABAergic sy
Jan 8，2024 Biochemical Engineering
Candesartan cilexetil in cardiovascular disease
Candesartan cilexetil is an oral angiotensin II receptor blocker. Candesartan is approved by the FDA for the treatment of hypertension in adults.
Jan 8，2024 Drugs
How to synthesize Brexanolone？
Developed by Sage Therapeutics, brexanolone was approved by the USFDA as a first-in-class treatment for PPD in adult women.
Jan 8，2024 API
What are the side effects of Valsartan?
ommon side effects of Valsartan include: shortness of breath, cough , dizziness and light-headedness on waking, nausea, fatigue, diarrhoea, skin irritation , postural hypotension, hyperkalaemia, and r
Jan 8，2024 Drugs
What is D-Xylose Absorption Test？
This test is done to help diagnose problems that prevent the small intestine from absorbing nutrients in food and evaluate the person’s ability to absorb carbohydrates in general.
Jan 8，2024 Biochemical Engineering
D-Biotin: Application; Side effects and Benefits
D-Biotin is a water-soluble enzyme cofactor that is present in trace amounts in every living cell. It binds primarily to proteins or peptides and is abundant in liver, kidney, pancreas, yeast and milk
Jan 8，2024 Vitamins and Minerals medicines
The role of Lithium bis(oxalate) borate as electrolyte additives
Lithium bis(oxalate) borate is one of the most widely used electrolyte additives in Li-ion batteries and has the potential to be an alternative for the commercially used lithium hexafluorophosphate (L
Jan 8，2024 Inorganic chemistry
2-Methyl-3-(3,4-methylenedioxyphenyl)propanal induces Ca2+ decrease and serotonin secretion via a PKG-mediated pathway
2-Methyl-3-(3,4-methylenedioxyphenyl)propanal can induce a dose-dependent decrease in Ca2+ levels in QGP-1 cells, potentially important for fragrance development and olfactory research.
Jan 8，2024 API
Synthesis of Tucatinib
Tucatinib was synthesised in a two-step reaction by an aniline fragment. Tucatinib is an orally bioavailable tyrosine kinase inhibitor of human epidermal growth factor receptor-2 (HER2 or ErbB2).
Jan 8，2024 Inhibitors
Thymine：a pyrimidine nucleobase
Thymine, a key DNA base. Its role s DNA structure, synthesis, and applications. Safety in natural context; isolated supplements lack established safety.
Jan 8，2024 Amino Acids and Proteins